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Do Soo Jang

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Articles 15
Citations 65
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Recent Articles
11.
Jang D, Lee H, Lee B, Hong B, Cha H, Yoon J, et al.
FEBS Lett . 2006 Jul; 580(17):4166-71. PMID: 16828747
Failure to detect the intermediate in spite of its existence often leads to the conclusion that two-state transition in the unfolding process of the protein can be justified. In contrast...
12.
Jang D, Cha H, Cha S, Hong B, Ha N, Lee J, et al.
Biochem J . 2004 Jul; 382(Pt 3):967-73. PMID: 15228388
KSI (ketosteroid isomerase) catalyses an allylic isomerization reaction at a diffusion-controlled rate. A hydrogen bond network, Asp(99).Water(504).Tyr(14).Tyr(55).Tyr(30), connects two critical catalytic residues, Tyr(14) and Asp(99), with Tyr(30), Tyr(55) and a...
13.
Nam G, Kim D, Ha N, Jang D, Yun Y, Hong B, et al.
J Biochem . 2003 Aug; 134(1):101-10. PMID: 12944376
Ketosteroid isomerase (KSI) from Pseudomonas putida biotype B is a homodimeric enzyme catalyzing an allylic isomerization of Delta(5)-3-ketosteroids at a rate of the diffusion-controlled limit. The dimeric interactions mediated by...
14.
Yun Y, Lee T, Nam G, Jang D, Shin S, Oh B, et al.
J Biol Chem . 2003 May; 278(30):28229-36. PMID: 12734184
Two homologous Delta5-3-ketosteroid isomerases from Comamonas testosteroni (TI-WT) and Pseudomonas putida biotype B (PI-WT) exhibit different pH activity profiles. TI-WT loses activity below pH 5.0 due to the protonation of...
15.
Yun S, Jang D, Choi G, Kim K, Choi K, Lee H
J Biol Chem . 2002 Apr; 277(26):23414-9. PMID: 11973332
In the equilibrium unfolding process of Delta(5)-3-ketosteroid isomerase from Pseudomonas testosteroni by urea, it was observed that the enzyme stability increases by 2.5 kcal/mol in the presence of 5% trifluoroethanol...