Dmitry M Shayakhmetov
Overview
Explore the profile of Dmitry M Shayakhmetov including associated specialties, affiliations and a list of published articles.
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59
Citations
2959
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Recent Articles
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Yao J, Atasheva S, Wagner N, Di Paolo N, Stewart P, Shayakhmetov D
Mol Ther
. 2024 Aug;
32(10):3743-3745.
PMID: 39178851
No abstract available.
3.
Kumar S, Biswas M, Cao D, Arisa S, Munoz-Melero M, Lam A, et al.
Mol Ther
. 2023 Dec;
32(2):325-339.
PMID: 38053332
Upon viral infection of the liver, CD8 T cell responses may be triggered despite the immune suppressive properties that manifest in this organ. We sought to identify pathways that activate...
4.
Yao J, Atasheva S, Wagner N, Di Paolo N, Stewart P, Shayakhmetov D
Mol Ther
. 2023 Nov;
32(1):103-123.
PMID: 37919899
Targeted delivery and cell-type-specific expression of gene-editing proteins in various cell types in vivo represent major challenges for all viral and non-viral delivery platforms developed to date. Here, we describe...
5.
Chen Z, Giotti B, Kaluzova M, Vallcorba M, Rawat K, Price G, et al.
J Clin Invest
. 2023 Sep;
133(22).
PMID: 37733448
Monocytes and monocyte-derived macrophages (MDMs) from blood circulation infiltrate glioblastoma (GBM) and promote growth. Here, we show that PDGFB-driven GBM cells induce the expression of the potent proinflammatory cytokine IL-1β...
6.
Structural Model for Factor X Inhibition of IgM and Complement-Mediated Neutralization of Adenovirus
Wagner N, Shayakhmetov D, Stewart P
Viruses
. 2023 Jun;
15(6).
PMID: 37376642
Adenovirus has strong therapeutic potential as an oncolytic virus and gene therapy vector. However, injecting human species C serotype 5 adenovirus, HAdv-C5, into the bloodstream leads to numerous interactions with...
7.
Yao J, Atasheva S, Toy R, Blanchard E, Santangelo P, Roy K, et al.
Sci Rep
. 2022 Sep;
12(1):16357.
PMID: 36175595
Pathogens trigger activation of sensors of the innate immune system that initiate molecular signaling enabling appropriate host defense programs. Although recognition of pathogen-specific moieties or PAMPs by specialized receptors of...
8.
Atasheva S, Shayakhmetov D
Viruses
. 2022 May;
14(5).
PMID: 35632630
The expression of cytokines and chemokines in response to adenovirus infection is tightly regulated by the innate immune system. Cytokine-mediated toxicity and cytokine storm are known clinical phenomena observed following...
9.
Coughlan L, Kremer E, Shayakhmetov D
Mol Ther
. 2022 Jan;
30(5):1822-1849.
PMID: 35092844
Zoonotic viruses continually pose a pandemic threat. Infection of humans with viruses for which we typically have little or no prior immunity can result in epidemics with high morbidity and...
10.
Atasheva S, Shayakhmetov D
Mol Ther
. 2021 Feb;
29(3):904-907.
PMID: 33577782
No abstract available.