Dmitry A Stetsenko
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Explore the profile of Dmitry A Stetsenko including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Lomzov A, Kupryushkin M, Shernyukov A, Nekrasov M, Dovydenko I, Stetsenko D, et al.
Biochem Biophys Res Commun
. 2019 Apr;
513(4):807-811.
PMID: 31000201
Recently, a new type of nucleic acid analogues with modified phosphate group, namely, phosphoryl guanidine oligonucleotides, has been described. In the present work, we assess the difference between diastereomers of...
12.
Su Y, Fujii H, Burakova E, Chelobanov B, Fujii M, Stetsenko D, et al.
Chem Asian J
. 2019 Jan;
14(8):1212-1220.
PMID: 30600926
The effect of phosphate group modifications on formation and properties of G-quadruplexes (G4s) has not been investigated in detail. Here, we evaluated the structural, thermodynamic and kinetic properties of the...
13.
Vasilyeva S, Grin I, Chelobanov B, Stetsenko D
Data Brief
. 2018 Oct;
21:540-547.
PMID: 30370324
SiO nanoparticles were used as a transport system for cellular delivery of phosphorylated 2',3'-dideoxyuridine to increase its anticancer potency. This data set is related to the research article entitled "2',3'-Dideoxyuridine...
14.
Vasilyeva S, Grin I, Chelobanov B, Stetsenko D
Bioorg Med Chem Lett
. 2018 Mar;
28(7):1248-1251.
PMID: 29506959
A conjugate of triphosphorylated 2',3'-dideoxyuridine (ddU) with SiO nanoparticles was obtained via the CuAAC click chemistry between a γ-alkynyl ddU triphosphate and azido-modified SiO nanoparticles. Assessment of cytotoxicity in human...
15.
Shinkai Y, Kashihara S, Minematsu G, Fujii H, Naemura M, Kotake Y, et al.
Nucleic Acid Ther
. 2017 Mar;
27(3):168-175.
PMID: 28355131
Herein we described the synthesis of siRNA-NES (nuclear export signal) peptide conjugates by solid phase fragment coupling and the application of them to silencing of bcr/abl chimeric gene in human...
16.
Vasilyeva S, Shtil A, Petrova A, Balakhnin S, Achigecheva P, Stetsenko D, et al.
Bioorg Med Chem
. 2017 Feb;
25(5):1696-1702.
PMID: 28169081
Conjugates of phosphorylated dideoxynucleoside antiviral drugs dideoxycytidine (zalcitabine) and lamivudine with SiO nanoparticles were obtained via the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry between a nucleoside triphosphate containing an alkynyl...
17.
Fokina A, Chelobanov B, Fujii M, Stetsenko D
Expert Opin Drug Deliv
. 2016 Nov;
14(9):1077-1089.
PMID: 27892730
Development of efficient in vivo delivery systems remains a major challenge en route to clinical application of antisense technology, including RNA-cleaving molecules such as deoxyribozymes (DNAzymes). The mechanisms of oligonucleotide...
18.
Kuznetsov N, Lebedeva N, Kuznetsova A, Rechkunova N, Dyrkheeva N, Kupryushkin M, et al.
J Biomol Struct Dyn
. 2016 Oct;
35(11):2314-2327.
PMID: 27687298
Tyrosyl-DNA phosphodiesterase 1 (Tdp1) processes DNA 3'-end-blocking modifications, possesses DNA and RNA 3'-nucleosidase activity and is also able to hydrolyze an internal apurinic/apyrimidinic (AP) site and its synthetic analogs. The...
19.
Kuznetsov N, Kupryushkin M, Abramova T, Kuznetsova A, Miroshnikova A, Stetsenko D, et al.
Mol Biosyst
. 2015 Nov;
12(1):67-75.
PMID: 26548492
Human apurinic/apyrimidinic endonuclease APE1 is one of the key enzymes of the base excision DNA repair system. The main biological function of APE1 is the hydrolysis of the phosphodiester bond...
20.
Vinogradova O, Lomzov A, Shevelev G, Sheglov D, Latyshev A, Stetsenko D, et al.
J Nanosci Nanotechnol
. 2015 Sep;
15(6):4170-7.
PMID: 26369026
Self-assembly of DNA concatemers from native duplexes and those containing non-nucleotidic bridges of varying polarity composed of repeating oligo(ethylene glycol) phosphates -O(CH2CH2O)(n)PO2- or α,Ω-alkanediol phosphates -O(CH2)10OPO2(-)- units was compared. The...