Dmitri V Pechkovsky
Overview
Explore the profile of Dmitri V Pechkovsky including associated specialties, affiliations and a list of published articles.
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18
Citations
1204
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Recent Articles
1.
Schuliga M, Pechkovsky D, Read J, Waters D, Blokland K, Reid A, et al.
J Cell Mol Med
. 2018 Sep;
22(12):5847-5861.
PMID: 30255990
Increasing evidence highlights that senescence plays an important role in idiopathic pulmonary fibrosis (IPF). This study delineates the specific contribution of mitochondria and the superoxide they form to the senescent...
2.
Schnerch J, Prasse A, Vlachakis D, Schuchardt K, Pechkovsky D, Goldmann T, et al.
Am J Respir Cell Mol Biol
. 2016 Jul;
55(5):749-757.
PMID: 27390897
Sarcoidosis is a granulomatous disease characterized by a T-helper type 1 (Th1) cell-dominated alveolitis. As a role of bacteria in the pathogenesis of sarcoidosis has been discussed, Toll-like receptors (TLRs)...
3.
Christenson S, Brandsma C, Campbell J, Knight D, Pechkovsky D, Hogg J, et al.
Genome Med
. 2014 Jan;
5(12):114.
PMID: 24380442
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by varying degrees of emphysematous lung destruction and small airway disease, each with distinct effects on clinical outcomes. There...
4.
Campbell J, McDonough J, Zeskind J, Hackett T, Pechkovsky D, Brandsma C, et al.
Genome Med
. 2012 Sep;
4(8):67.
PMID: 22937864
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. Methods:...
5.
Pechkovsky D, Prele C, Wong J, Hogaboam C, McAnulty R, Laurent G, et al.
Am J Pathol
. 2012 Feb;
180(4):1398-412.
PMID: 22322297
STAT3 is a latent transcription factor that plays a role in regulating fibroblast function in fibrotic lung diseases. To further understand the role of STAT3 in the phenotypic divergence and...
6.
Cooper D, Pechkovsky D, Hackett T, Knight D, Granville D
PLoS One
. 2011 Jul;
6(6):e21484.
PMID: 21760880
Granzyme K (GrK) is a trypsin-like serine protease that is elevated in patients with sepsis and acute lung inflammation. While GrK was originally believed to function exclusively as a pro-apoptotic...
7.
Abraham T, Wadsworth S, Carthy J, Pechkovsky D, McManus B
Respirology
. 2010 Nov;
16(1):22-33.
PMID: 21054675
For translational respiratory research including in the development of clinical diagnostic tools, a minimally invasive imaging method, which can provide both cellular and extracellular structural details with sufficient specificity, sensitivity...
8.
Pechkovsky D, Prasse A, Kollert F, Engel K, Dentler J, Luttmann W, et al.
Clin Immunol
. 2010 Aug;
137(1):89-101.
PMID: 20674506
Activated macrophages have been characterized as M1 and M2 according to their inflammatory response pattern. Here we analyzed the M2 marker expression and intracellular signal transduction in the course of...
9.
Pechkovsky D, Hackett T, An S, Shaheen F, Murray L, Knight D
Am J Respir Cell Mol Biol
. 2010 Jan;
43(6):641-51.
PMID: 20061511
Given the contribution various fibroblast subsets make to wound healing and tissue remodeling, the concept of lung fibroblast heterogeneity is of great interest. However, the mechanisms contributing to this heterogeneity...
10.
Hackett T, Warner S, Stefanowicz D, Shaheen F, Pechkovsky D, Murray L, et al.
Am J Respir Crit Care Med
. 2009 May;
180(2):122-33.
PMID: 19406982
Rationale: Airway remodeling in asthma is associated with the accumulation of fibroblasts, the primary cell responsible for synthesis and secretion of extracellular matrix proteins. The process by which the number...