Dmitri Lodygin
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Explore the profile of Dmitri Lodygin including associated specialties, affiliations and a list of published articles.
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22
Citations
2064
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Recent Articles
1.
Markusson S, Raasakka A, Schroder M, Sograte-Idrissi S, Rahimi A, Asadpour O, et al.
J Neurochem
. 2024 Dec;
169(1):e16274.
PMID: 39655780
2',3'-Cyclic nucleotide 3'-phosphodiesterase (CNPase) is an abundant constituent of central nervous system non-compact myelin, and its loss in mice and humans causes neurodegeneration. Additionally, CNPase is frequently used as a...
2.
Shumanska M, Lodygin D, Gibhardt C, Ickes C, Stejerean-Todoran I, Krause L, et al.
EMBO Rep
. 2024 Dec;
26(2):407-442.
PMID: 39623165
T-cell receptor (TCR)-induced Ca signals are essential for T-cell activation and function. In this context, mitochondria play an important role and take up Ca to support elevated bioenergetic demands. However,...
3.
Markusson S, Raasakka A, Schroder M, Sograte-Idrissi S, Rahimi A, Asadpour O, et al.
bioRxiv
. 2024 Jun;
PMID: 38826303
2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) is an abundant constituent of central nervous system non-compact myelin, frequently used as a marker antigen for myelinating cells. The catalytic activity of CNPase, the 3'-hydrolysis...
4.
Bagnoud M, Remlinger J, Massy M, Lodygin D, Salmen A, Chan A, et al.
Cells
. 2023 Sep;
12(18).
PMID: 37759513
Our previous work demonstrated that vitamin D (VitD) reduces experimental autoimmune encephalomyelitis (EAE) disease severity in wild-type (WT) but not in T cell-specific glucocorticoid (GC) receptor (GR)-deficient (GR) mice. This...
5.
Gu F, Kruger A, Roggenkamp H, Alpers R, Lodygin D, Jaquet V, et al.
Sci Signal
. 2021 Nov;
14(709):eabe3800.
PMID: 34784249
The formation of Ca microdomains during T cell activation is initiated by the production of nicotinic acid adenine dinucleotide phosphate (NAADP) from its reduced form NAADPH. The reverse reaction—NAADP to...
6.
Roggenkamp H, Khansahib I, Hernandez C L, Zhang Y, Lodygin D, Kruger A, et al.
Sci Signal
. 2021 Mar;
14(675).
PMID: 33758062
NAADP-evoked Ca release through type 1 ryanodine receptors (RYR1) is a major mechanism underlying the earliest signals in T cell activation, which are the formation of Ca microdomains. In our...
7.
Lodygin D, Hermann M, Schweingruber N, Flugel-Koch C, Watanabe T, Schlosser C, et al.
Nature
. 2019 Mar;
567(7749):E15.
PMID: 30867589
In this Article, owing to an error during the production process, the y-axis label of Fig. 2c should read "Number of T cells" rather than "Number of T1 cells" and...
8.
Lodygin D, Hermann M, Schweingruber N, Flugel-Koch C, Watanabe T, Schlosser C, et al.
Nature
. 2019 Feb;
566(7745):503-508.
PMID: 30787438
The grey matter is a central target of pathological processes in neurodegenerative disorders such as Parkinson's and Alzheimer's diseases. The grey matter is often also affected in multiple sclerosis, an...
9.
Diercks B, Werner R, Weidemuller P, Czarniak F, Hernandez L, Lehmann C, et al.
Sci Signal
. 2018 Dec;
11(561).
PMID: 30563862
The earliest intracellular signals that occur after T cell activation are local, subsecond Ca microdomains. Here, we identified a Ca entry component involved in Ca microdomain formation in both unstimulated...
10.
Luhder F, Kebir H, Odoardi F, Litke T, Sonneck M, Ivan Alvarez J, et al.
Neurobiol Dis
. 2017 Feb;
102:60-69.
PMID: 28235673
Laquinimod is currently being tested as a therapeutic drug in multiple sclerosis. However, its exact mechanism of action is still under investigation. Tracking of fluorescently-tagged encephalitogenic T cells during experimental...