Divya Bezwada
Overview
Explore the profile of Divya Bezwada including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
22
Citations
913
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Zhang Y, Liu Z, Hirschi M, Brodsky O, Johnson E, Won S, et al.
Nat Chem Biol
. 2024 Sep;
21(3):420-431.
PMID: 39294320
More than half of the ~20,000 protein-encoding human genes have paralogs. Chemical proteomics has uncovered many electrophile-sensitive cysteines that are exclusive to subsets of paralogous proteins. Here we explore whether...
2.
Bezwada D, Perelli L, Lesner N, Cai L, Brooks B, Wu Z, et al.
Nature
. 2024 Aug;
633(8031):923-931.
PMID: 39143213
Most kidney cancers are metabolically dysfunctional, but how this dysfunction affects cancer progression in humans is unknown. We infused C-labelled nutrients in over 80 patients with kidney cancer during surgical...
3.
Wu Z, Bezwada D, Cai F, Harris R, Ko B, Sondhi V, et al.
Cell Metab
. 2024 Jun;
36(7):1504-1520.e9.
PMID: 38876105
Mitochondria house many metabolic pathways required for homeostasis and growth. To explore how human cells respond to mitochondrial dysfunction, we performed metabolomics in fibroblasts from patients with various mitochondrial disorders...
4.
Wang X, Menezes C, Jia Y, Xiao Y, Venigalla S, Cai F, et al.
Science
. 2024 Jun;
384(6701):eadj4301.
PMID: 38870309
Mitochondria are critical for proper organ function and mechanisms to promote mitochondrial health during regeneration would benefit tissue homeostasis. We report that during liver regeneration, proliferation is suppressed in electron...
5.
Tran D, Kim D, Kesavan R, Brown H, Dey T, Soflaee M, et al.
Cell
. 2024 Jun;
187(14):3602-3618.e20.
PMID: 38823389
Purine nucleotides are vital for RNA and DNA synthesis, signaling, metabolism, and energy homeostasis. To synthesize purines, cells use two principal routes: the de novo and salvage pathways. Traditionally, it...
6.
Calhoon D, Sang L, Bezwada D, Kim N, Basu A, Hsu S, et al.
bioRxiv
. 2024 May;
PMID: 38765991
Lipids are essential for tumours because of their structural, energetic, and signaling roles. While many cancer cells upregulate lipid synthesis, growing evidence suggests that tumours simultaneously intensify the uptake of...
7.
Mukherjee A, Bezwada D, Greco F, Zandbergen M, Shen T, Chiang C, et al.
Nat Metab
. 2023 Aug;
5(9):1563-1577.
PMID: 37653041
In the tumor microenvironment, adipocytes function as an alternate fuel source for cancer cells. However, whether adipocytes influence macromolecular biosynthesis in cancer cells is unknown. Here we systematically characterized the...
8.
Cai F, Bezwada D, Cai L, Mahar R, Wu Z, Chang M, et al.
Cell Metab
. 2023 Aug;
35(10):1830-1843.e5.
PMID: 37611583
Stable isotopes are powerful tools to assess metabolism. C labeling is detected using nuclear magnetic resonance (NMR) spectroscopy or mass spectrometry (MS). MS has excellent sensitivity but generally cannot discriminate...
9.
Bezwada D, Brugarolas J
J Clin Invest
. 2023 Jun;
133(11).
PMID: 37259915
Fumarate hydratase-deficient (FH-deficient) renal cell carcinoma (RCC) represents a particularly aggressive form of kidney cancer. FH-deficient RCC arises in the setting of germline, or solely somatic, mutations in the FH...
10.
Wu Z, Bezwada D, Harris R, Pan C, Nguyen P, Faubert B, et al.
bioRxiv
. 2023 May;
PMID: 37214913
Cancer cells reprogram their metabolism to support cell growth and proliferation in harsh environments. While many studies have documented the importance of mitochondrial oxidative phosphorylation (OXPHOS) in tumor growth, some...