Dimitris Skokos
Overview
Explore the profile of Dimitris Skokos including associated specialties, affiliations and a list of published articles.
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34
Citations
1649
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Recent Articles
1.
Petro C, Hooper A, Peace A, Mohammadi K, Eagan W, Elbashir S, et al.
Sci Transl Med
. 2024 Nov;
16(772):eadn0396.
PMID: 39504352
Increased use of antiviral monoclonal antibodies (mAbs) for treatment and prophylaxis necessitates better understanding of their impact on endogenous immunity to vaccines and viruses. The severe acute respiratory syndrome coronavirus...
2.
Wang B, Golubov J, Oswald E, Poon P, Wei Q, Lett C, et al.
EBioMedicine
. 2024 Sep;
108:105334.
PMID: 39270622
Background: Passive administration of SARS-CoV-2 neutralizing monoclonal antibodies (mAbs), such as CAS + IMD (Casirivimab + Imdevimab) antibody cocktail demonstrated beneficial effects on clinical outcomes in hospitalized patients with COVID-19...
3.
Lotze M, Olejniczak S, Skokos D
Nat Rev Immunol
. 2024 Jul;
24(12):878-895.
PMID: 39054343
Substantial progress in understanding T cell signalling, particularly with respect to T cell co-receptors such as the co-stimulatory receptor CD28, has been made in recent years. This knowledge has been...
4.
Leary A, Scott D, Gupta N, Waite J, Skokos D, Atwal G, et al.
Nat Commun
. 2024 May;
15(1):4271.
PMID: 38769289
T Cell Receptor (TCR) antigen binding underlies a key mechanism of the adaptive immune response yet the vast diversity of TCRs and the complexity of protein interactions limits our ability...
5.
Ebstein S, Rafique A, Zhou Y, Krasco A, Montalvo-Ortiz W, Yu L, et al.
Glycobiology
. 2023 Jun;
33(7):591-604.
PMID: 37341346
V-set and immunoglobulin domain-containing 4 (VSIG4) is a complement receptor of the immunoglobulin superfamily that is specifically expressed on tissue resident macrophages, and its many reported functions and binding partners...
6.
Kwart D, He J, Srivatsan S, Lett C, Golubov J, Oswald E, et al.
Cell Rep
. 2022 Dec;
41(10):111769.
PMID: 36476866
Monocytes are highly plastic immune cells that modulate antitumor immunity. Therefore, identifying factors that regulate tumor monocyte functions is critical for developing effective immunotherapies. Here, we determine that endogenous cancer...
7.
Wei J, Montalvo-Ortiz W, Yu L, Krasco A, Olson K, Rizvi S, et al.
Sci Transl Med
. 2022 Nov;
14(670):eabn1082.
PMID: 36350988
Although many patients with diffuse large B cell lymphoma (DLBCL) may achieve a complete response to frontline chemoimmunotherapy, patients with relapsed/refractory disease typically have poor outcomes. Odronextamab, a CD20xCD3 bispecific...
8.
Kourtis N, Wang Q, Wang B, Oswald E, Adler C, Cherravuru S, et al.
Nat Cancer
. 2022 Jun;
3(7):885-898.
PMID: 35668194
A complete chart of the chromatin regulatory elements of immune cells in patients with cancer and their dynamic behavior is necessary to understand the developmental fates and guide therapeutic strategies....
9.
Wei J, Montalvo-Ortiz W, Yu L, Krasco A, Ebstein S, Cortez C, et al.
Sci Immunol
. 2021 Apr;
6(58).
PMID: 33837124
Although radiotherapy has been used for over a century to locally control tumor growth, alone it rarely induces an abscopal response or systemic antitumor immunity capable of inhibiting distal tumors...
10.
Ye X, Waite J, Dhanik A, Gupta N, Zhong M, Adler C, et al.
Oncoimmunology
. 2020 Sep;
9(1):1758602.
PMID: 32923116
Clinical observations suggest that responses to cancer immunotherapy are correlated with intra-tumoral T cell receptor (TCR) clonality, tumor mutation burden (TMB) and host HLA genotype, highlighting the importance of host...