Dimitris Polychronopoulos
Overview
Explore the profile of Dimitris Polychronopoulos including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
448
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Recent Articles
1.
Krithara A, Nentidis A, Vandorou E, Katsimpras G, Almirantis Y, Arnal M, et al.
J Am Med Inform Assoc
. 2024 Aug;
31(11):2689-2698.
PMID: 39180335
Objective: This article presents the novel BioASQ Synergy research process which aims to facilitate the interaction between biomedical experts and automated question-answering systems. Materials And Methods: The proposed research allows...
2.
Polychronopoulos D, Nguyen-Duc A
F1000Res
. 2023 Dec;
12:1300.
PMID: 38046194
Background: This systematic literature review (SLR) analyzes migrant entrepreneurship support in Europe through three research questions (RQs) to understand 1) migrant entrepreneur characteristics in the European context, 2) challenges encountered...
3.
Nakken S, Gundersen S, Bernal F, Polychronopoulos D, Hovig E, Wesche J
Int J Cancer
. 2023 Aug;
153(10):1819-1828.
PMID: 37551617
Genome-scale screening experiments in cancer produce long lists of candidate genes that require extensive interpretation for biological insight and prioritization for follow-up studies. Interrogation of gene lists frequently represents a...
4.
Gogleva A, Polychronopoulos D, Pfeifer M, Poroshin V, Ughetto M, Martin M, et al.
Nat Commun
. 2022 Mar;
13(1):1667.
PMID: 35351890
Resistance to EGFR inhibitors (EGFRi) presents a major obstacle in treating non-small cell lung cancer (NSCLC). One of the most exciting new ways to find potential resistance markers involves running...
5.
Smedley D, Smith K, Martin A, Thomas E, McDonagh E, Cipriani V, et al.
N Engl J Med
. 2021 Nov;
385(20):1868-1880.
PMID: 34758253
Background: The U.K. 100,000 Genomes Project is in the process of investigating the role of genome sequencing in patients with undiagnosed rare diseases after usual care and the alignment of...
6.
Tan G, Polychronopoulos D, Lenhard B
PLoS Comput Biol
. 2019 Aug;
15(8):e1006940.
PMID: 31449516
Conserved Noncoding Elements (CNEs) are elements exhibiting extreme noncoding conservation in Metazoan genomes. They cluster around developmental genes and act as long-range enhancers, yet nothing that we know about their...
7.
Apostolou-Karampelis K, Polychronopoulos D, Almirantis Y
Sci Rep
. 2019 Feb;
9(1):1700.
PMID: 30737442
Analysis of DNA composition at several length scales constitutes the bulk of many early studies aimed at unravelling the complexity of the organization and functionality of genomes. Dinucleotide relative abundances...
8.
Ayad L, Pissis S, Polychronopoulos D
Bioinformatics
. 2018 Nov;
34(17):i743-i747.
PMID: 30423090
Motivation: Conserved non-coding elements (CNEs) represent an enigmatic class of genomic elements which, despite being extremely conserved across evolution, do not encode for proteins. Their functions are still largely unknown....
9.
Polychronopoulos D, King J, Nash A, Tan G, Lenhard B
Nucleic Acids Res
. 2017 Nov;
45(22):12611-12624.
PMID: 29121339
Comparative genomics has revealed a class of non-protein-coding genomic sequences that display an extraordinary degree of conservation between two or more organisms, regularly exceeding that found within protein-coding exons. These...
10.
Almirantis Y, Charalampopoulos P, Gao J, Iliopoulos C, Mohamed M, Pissis S, et al.
Algorithms Mol Biol
. 2017 Mar;
12:5.
PMID: 28293277
Background: The deviation of the observed frequency of a word from its expected frequency in a given sequence is used to determine whether or not the word is . This...