Dimitrios Valakos
Overview
Explore the profile of Dimitrios Valakos including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
49
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0
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Recent Articles
1.
Klagkou E, Valakos D, Foutadakis S, Polyzos A, Papadopoulou A, Vatsellas G, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684837
Cellular reprogramming of somatic cells towards induced pluripotency is a multistep stochastic process mediated by the transcription factors Oct4, Sox2, Klf4 and c-Myc (OSKM), which orchestrate global epigenetic and transcriptional...
2.
Angelopoulou A, Theocharous G, Valakos D, Polyzou A, Magkouta S, Myrianthopoulos V, et al.
Mol Cancer
. 2024 Jul;
23(1):147.
PMID: 39048991
Non-small cell lung cancer (NSCLC) constitutes one of the deadliest and most common malignancies. The LKB1/STK11 tumour suppressor is mutated in ∼ 30% of NSCLCs, typically lung adenocarcinomas (LUAD). We...
3.
Efentakis P, Symeonidi L, Gianniou D, Mikropoulou E, Giardoglou P, Valakos D, et al.
Nutrients
. 2024 Jul;
16(13).
PMID: 38999899
Hypertension poses a significant global health burden and is associated with cardiovascular morbidity. Chios mastic gum (CMG), derived from var. , shows potential as a phytotherapeutic agent, due to its...
4.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, et al.
STAR Protoc
. 2024 Mar;
5(1):102929.
PMID: 38460134
Identification and isolation of senescent cells is challenging, rendering their detailed analysis an unmet need. We describe a precise one-step protocol to fluorescently label senescent cells, for flow cytometry and...
5.
Ntoulas G, Brakatselos C, Nakas G, Asprogerakas M, Delis F, Leontiadis L, et al.
Transl Psychiatry
. 2024 Feb;
14(1):104.
PMID: 38378836
Fragile X syndrome (FXS) is the most common cause of inherited intellectual disabilities and the most prevalent monogenic cause of autism. Although the knockout (KO) of the Fmr1 gene homolog...
6.
Veroutis D, Argyropoulou O, Goules A, Kambas K, Palamidas D, Evangelou K, et al.
Ann Rheum Dis
. 2023 Dec;
83(3):342-350.
PMID: 38050005
Objectives: Age is the strongest risk factor of giant cell arteritis (GCA), implying a possible pathogenetic role of cellular senescence. To address this question, we applied an established senescence specific...
7.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, et al.
Mol Cell
. 2023 Oct;
83(19):3558-3573.e7.
PMID: 37802028
Cellular senescence is a stress-response mechanism implicated in various physiological processes, diseases, and aging. Current detection approaches have partially addressed the issue of senescent cell identification in clinical specimens. Effective...
8.
Katsouda A, Valakos D, Vatsellas G, Thanos D, Papapetropoulos A
STAR Protoc
. 2023 Sep;
4(4):102594.
PMID: 37742172
Chromatin immunoprecipitation (ChIP) protocols have been used to reveal protein-DNA interactions of various cell types and tissues; however, optimization is required for each specific type of sample. Here, we present...
9.
Drosos Y, Konstantakou E, Bassogianni A, Nikolakopoulos K, Koumoundourou D, Markaki S, et al.
Cancers (Basel)
. 2023 Jul;
15(14).
PMID: 37509392
Bladder cancer (BLCA) is the sixth most common type of cancer and has a dismal prognosis if diagnosed late. To identify treatment options for BLCA, we systematically evaluated data from...
10.
Valakos D, Klagkou E, Kokkalis A, Polyzos A, Kyrilis F, Banos A, et al.
PLoS One
. 2023 Jul;
18(7):e0288005.
PMID: 37432970
Generation of induced pluripotent stem cells from specialized cell types provides an excellent model to study how cells maintain their stability, and how they can change identity, especially in the...