Aikaterini Polyzou
Overview
Explore the profile of Aikaterini Polyzou including associated specialties, affiliations and a list of published articles.
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22
Citations
255
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Recent Articles
1.
Hidaoui D, Porquet A, Chelbi R, Bohm M, Polyzou A, Alcazer V, et al.
Commun Biol
. 2024 Nov;
7(1):1555.
PMID: 39578583
Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy affecting the elderly, for which therapeutic options are limited. DNA hypomethylating agents (HMAs) provide transient responses, failing to eradicate the malignant...
2.
Greiner-Tollersrud O, Krausz M, Boehler V, Polyzou A, Seidl M, Spahiu A, et al.
Cell Rep
. 2024 Oct;
43(11):114899.
PMID: 39441717
Although adenosine deaminase 2 (ADA2) is considered an extracellular ADA, evidence questions the physiological relevance of this activity. Our study reveals that ADA2 localizes within the lysosomes, where it is...
3.
Angelopoulou A, Theocharous G, Valakos D, Polyzou A, Magkouta S, Myrianthopoulos V, et al.
Mol Cancer
. 2024 Jul;
23(1):147.
PMID: 39048991
Non-small cell lung cancer (NSCLC) constitutes one of the deadliest and most common malignancies. The LKB1/STK11 tumour suppressor is mutated in ∼ 30% of NSCLCs, typically lung adenocarcinomas (LUAD). We...
4.
Pantelis P, Theocharous G, Veroutis D, Vagena I, Polyzou A, Thanos D, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473720
The currently available anti-cancer therapies, such as gamma-radiation and chemotherapeutic agents, induce cell death and cellular senescence not only in cancer cells but also in the adjacent normal tissue. New...
5.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Giannetti K, Pippa N, et al.
STAR Protoc
. 2024 Mar;
5(1):102929.
PMID: 38460134
Identification and isolation of senescent cells is challenging, rendering their detailed analysis an unmet need. We describe a precise one-step protocol to fluorescently label senescent cells, for flow cytometry and...
6.
Veroutis D, Argyropoulou O, Goules A, Kambas K, Palamidas D, Evangelou K, et al.
Ann Rheum Dis
. 2023 Dec;
83(3):342-350.
PMID: 38050005
Objectives: Age is the strongest risk factor of giant cell arteritis (GCA), implying a possible pathogenetic role of cellular senescence. To address this question, we applied an established senescence specific...
7.
Magkouta S, Veroutis D, Pousias A, Papaspyropoulos A, Pippa N, Lougiakis N, et al.
Mol Cell
. 2023 Oct;
83(19):3558-3573.e7.
PMID: 37802028
Cellular senescence is a stress-response mechanism implicated in various physiological processes, diseases, and aging. Current detection approaches have partially addressed the issue of senescent cell identification in clinical specimens. Effective...
8.
Papaspyropoulos A, Hazapis O, Altulea A, Polyzou A, Verginis P, Evangelou K, et al.
Aging Cell
. 2023 Aug;
22(9):e13893.
PMID: 37547972
Cellular senescence constitutes a generally irreversible proliferation barrier, accompanied by macromolecular damage and metabolic rewiring. Several senescence types have been identified based on the initiating stimulus, such as replicative (RS),...
9.
Mourkioti I, Polyzou A, Veroutis D, Theocharous G, Lagopati N, Gentile E, et al.
J Exp Clin Cancer Res
. 2023 Jul;
42(1):187.
PMID: 37507762
Background: Prostate cancer is a major cause of cancer morbidity and mortality in men worldwide. Androgen deprivation therapy (ADT) has proven effective in early-stage androgen-sensitive disease, but prostate cancer gradually...
10.
Schuster E, Epple M, Glaser K, Mihlan M, Lucht K, Zimmermann J, et al.
Nat Metab
. 2022 Jul;
4(7):856-866.
PMID: 35864246
Successful elimination of bacteria in phagocytes occurs in the phago-lysosomal system, but also depends on mitochondrial pathways. Yet, how these two organelle systems communicate is largely unknown. Here we identify...