Diana C Haines
Overview
Explore the profile of Diana C Haines including associated specialties, affiliations and a list of published articles.
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40
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2236
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Recent Articles
1.
Szot C, Saha S, Zhang X, Zhu Z, Hilton M, Morris K, et al.
J Clin Invest
. 2018 Jun;
128(7):2927-2943.
PMID: 29863500
Although nonmalignant stromal cells facilitate tumor growth and can occupy up to 90% of a solid tumor mass, better strategies to exploit these cells for improved cancer therapy are needed....
2.
Antony S, Jiang G, Wu Y, Meitzler J, Makhlouf H, Haines D, et al.
Mol Carcinog
. 2017 Aug;
56(12):2643-2662.
PMID: 28762556
NADPH oxidase 5 (NOX5) generated reactive oxygen species (ROS) have been implicated in signaling cascades that regulate cancer cell proliferation. To evaluate and validate NOX5 expression in human tumors, we...
3.
Yang Y, Yang H, Hu Y, Watson P, Liu H, Geiger T, et al.
Oncotarget
. 2017 Apr;
8(19):30621-30643.
PMID: 28430642
Effective drug development to combat metastatic disease in breast cancer would be aided by the availability of well-characterized preclinical animal models that (a) metastasize with high efficiency, (b) metastasize in...
4.
Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al.
J Biol Chem
. 2017 Mar;
292(19):7866-7887.
PMID: 28330872
Reactive oxygen species (ROS) play a critical role in cell signaling and proliferation. NADPH oxidase 1 (NOX1), a membrane-bound flavin dehydrogenase that generates O, is highly expressed in colon cancer....
5.
Song Y, Sullivan T, Klarmann K, Gilbert D, OSullivan T, Lu L, et al.
PLoS One
. 2017 Feb;
12(2):e0171510.
PMID: 28158249
Thymic epithelial cells (TEC), as part of thymic stroma, provide essential growth factors/cytokines and self-antigens to support T cell development and selection. Deletion of Rb family proteins in adult thymic...
6.
Hasumi H, Hasumi Y, Baba M, Nishi H, Furuya M, Vocke C, et al.
Hum Mol Genet
. 2016 Dec;
26(2):354-366.
PMID: 28007907
Germline H255Y and K508R missense mutations in the folliculin (FLCN) gene have been identified in patients with bilateral multifocal (BMF) kidney tumours and clinical manifestations of Birt-Hogg-Dubé (BHD) syndrome, or...
7.
Wu Y, Meitzler J, Antony S, Juhasz A, Lu J, Jiang G, et al.
Oncotarget
. 2016 Sep;
7(42):68412-68433.
PMID: 27637085
Several NADPH oxidase family members, including dual oxidase 2 [DUOX2], are expressed in human tumors, particularly gastrointestinal cancers associated with long-standing chronic inflammation. We found previously that exposure of pancreatic...
8.
Hartford S, Chittela R, Ding X, Vyas A, Martin B, Burkett S, et al.
PLoS Genet
. 2016 Aug;
12(8):e1006236.
PMID: 27490902
Human breast cancer susceptibility gene, BRCA2, encodes a 3418-amino acid protein that is essential for maintaining genomic integrity. Among the proteins that physically interact with BRCA2, Partner and Localizer of...
9.
Thirthagiri E, Klarmann K, Shukla A, Southon E, Biswas K, Martin B, et al.
Hum Mol Genet
. 2016 Feb;
25(10):1934-1945.
PMID: 26920070
The breast cancer gene, BRCA2, is essential for viability, yet patients with Fanconi anemia-D1 subtype are born alive with biallelic mutations in this gene. The hypomorphic nature of the mutations...
10.
Kim S, Song J, Kim S, Qu P, Martin B, Sehareen W, et al.
Oncotarget
. 2016 Feb;
7(10):11094-112.
PMID: 26848978
The oncogenic role of microRNA-155 (miR-155) in leukemia is well established but its role in other cancers, especially breast cancer, is gradually emerging. In this study we examined the effect...