Devika P Bagchi
Overview
Explore the profile of Devika P Bagchi including associated specialties, affiliations and a list of published articles.
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22
Citations
930
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Recent Articles
1.
Vohnoutka R, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme M, et al.
J Mol Endocrinol
. 2023 Feb;
70(3).
PMID: 36748836
Human genome-wide association studies found single-nucleotide polymorphisms (SNPs) near LYPLAL1 (Lysophospholipase-like protein 1) that have sex-specific effects on fat distribution and metabolic traits. To determine whether altering LYPLAL1 affects obesity...
2.
Li Z, Bagchi D, Zhu J, Bowers E, Yu H, Hardij J, et al.
JCI Insight
. 2022 Sep;
7(21).
PMID: 36048537
BM adipocytes (BMAd) are a unique cell population derived from BM mesenchymal progenitors and marrow adipogenic lineage precursors. Although they have long been considered to be a space filler within...
3.
Li Z, Bowers E, Zhu J, Yu H, Hardij J, Bagchi D, et al.
Elife
. 2022 Jun;
11.
PMID: 35731039
To investigate roles for bone marrow adipocyte (BMAd) lipolysis in bone homeostasis, we created a BMAd-specific Cre mouse model in which we knocked out adipose triglyceride lipase (ATGL, gene). BMAd-...
4.
Bagchi D, MacDougald O
Diabetes
. 2021 Jun;
70(7):1419-1430.
PMID: 34155042
Wnt signaling is an ancient and evolutionarily conserved pathway with fundamental roles in the development of adipose tissues. Roles of this pathway in mesenchymal stem cell fate determination and differentiation...
5.
Corsa C, Walsh C, Bagchi D, Foss Freitas M, Li Z, Hardij J, et al.
Diabetes
. 2021 Jun;
70(9):1970-1984.
PMID: 34088712
Mechanisms by which autosomal recessive mutations in cause familial partial lipodystrophy type 2 (FPLD2) are poorly understood. To investigate the function of lamin A/C in adipose tissue, we created mice...
6.
The molecular and metabolic program by which white adipocytes adapt to cool physiologic temperatures
Mori H, Dugan C, Nishii A, Benchamana A, Li Z, Cadenhead 4th T, et al.
PLoS Biol
. 2021 May;
19(5):e3000988.
PMID: 33979328
Although visceral adipocytes located within the body's central core are maintained at approximately 37°C, adipocytes within bone marrow, subcutaneous, and dermal depots are found primarily within the peripheral shell and...
7.
Cote J, Argetsinger L, Flores A, Rupp A, Cline J, DeSantis L, et al.
Diabetes
. 2020 Nov;
70(2):400-414.
PMID: 33214137
Mice lacking SH2B1 and humans with variants of SH2B1 display severe obesity and insulin resistance. SH2B1 is an adapter protein that is recruited to the receptors of multiple hormones and...
8.
Bagchi D, Nishii A, Li Z, Delproposto J, Corsa C, Mori H, et al.
Mol Metab
. 2020 Sep;
42:101078.
PMID: 32919095
Objective: Canonical Wnt/β-catenin signaling is a well-studied endogenous regulator of mesenchymal cell fate determination, promoting osteoblastogenesis and inhibiting adipogenesis. However, emerging genetic evidence in humans links a number of Wnt...
9.
Bagchi D, Li Z, Corsa C, Hardij J, Mori H, Learman B, et al.
Mol Metab
. 2020 Apr;
39:100992.
PMID: 32325263
Objective: Obesity is a key risk factor for many secondary chronic illnesses, including type 2 diabetes and cardiovascular disease. Canonical Wnt/β-catenin signaling is established as an important endogenous inhibitor of...
10.
Chen N, Schill R, ODonnell M, Xu K, Bagchi D, MacDougald O, et al.
J Biol Chem
. 2019 Oct;
294(48):18408-18420.
PMID: 31615896
Although adipogenesis is mainly controlled by a small number of master transcription factors, including CCAAT/enhancer-binding protein family members and peroxisome proliferator-activated receptor γ (PPARγ), other transcription factors also are involved...