Derek J Nancarrow
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Explore the profile of Derek J Nancarrow including associated specialties, affiliations and a list of published articles.
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28
Citations
534
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Recent Articles
21.
Tyagi S, Stark M, Hayward N, Whiteman D, Nancarrow D
Biochem Biophys Res Commun
. 2010 Sep;
401(3):447-50.
PMID: 20869951
A large number of new genomic features are being discovered using high throughput techniques. The next challenge is to automatically map them to the reference genome for further analysis and...
22.
Antonsson A, Nancarrow D, Brown I, Green A, Drew P, Watson D, et al.
Cancer Epidemiol Biomarkers Prev
. 2010 Aug;
19(8):2080-7.
PMID: 20696664
Background: Although most cases of esophageal squamous cell carcinoma (ESCC) in western populations have been attributed to high levels of exposure to tobacco and alcohol, infectious agents have been postulated...
23.
Botelho N, Schneiders F, Lord S, Freeman A, Tyagi S, Nancarrow D, et al.
Cancer Biol Ther
. 2010 Jun;
10(2):172-9.
PMID: 20543560
Background And Aim: Widespread applicability of tissue-based mRNA expression screening for Barrett esophagus (BE) is likely to require (1) accurate methods for assaying archival formalin-fixed, paraffin-embedded (FFPE) histopathology specimens taken...
24.
Stark M, Tyagi S, Nancarrow D, Boyle G, Cook A, Whiteman D, et al.
PLoS One
. 2010 Mar;
5(3):e9685.
PMID: 20300190
Background: MicroRNAs (miRNAs) are 18-23 nucleotide non-coding RNAs that regulate gene expression in a sequence specific manner. Little is known about the repertoire and function of miRNAs in melanoma or...
25.
Smith E, De Young N, Pavey S, Hayward N, Nancarrow D, Whiteman D, et al.
Mol Cancer
. 2008 Oct;
7:75.
PMID: 18831746
Background: Barrett's esophagus (BE) is the metaplastic replacement of squamous with columnar epithelium in the esophagus, as a result of reflux. It is the major risk factor for the development...
26.
Holliday E, Nyholt D, Tirupati S, John S, Ramachandran P, Ramamurti M, et al.
Am J Psychiatry
. 2008 Oct;
166(2):206-15.
PMID: 18829870
Objective: The study of ethnically homogeneous populations may help to identify schizophrenia risk loci. The authors conducted a genomewide linkage scan for schizophrenia in an Indian population. Method: Participants were...
27.
Nancarrow D, Handoko H, Smithers B, Gotley D, Drew P, Watson D, et al.
Cancer Res
. 2008 Jun;
68(11):4163-72.
PMID: 18519675
We applied whole-genome single-nucleotide polymorphism arrays to define a comprehensive genetic profile of 23 esophageal adenocarcinoma (EAC) primary tumor biopsies based on loss of heterozygosity (LOH) and DNA copy number...
28.
Nancarrow D, Handoko H, Stark M, Whiteman D, Hayward N
PLoS One
. 2007 Nov;
2(10):e1093.
PMID: 17971856
The recent application of genome-wide, single nucleotide polymorphism (SNP) microarrays to investigate DNA copy number aberrations in cancer has provided unparalleled sensitivity for identifying genomic changes. In some instances the...
29.
Handoko H, Nancarrow D, Hayward N, Ohaeri J, Aghanwa H, McGrath J, et al.
Am J Med Genet B Neuropsychiatr Genet
. 2003 Aug;
121B(1):1-6.
PMID: 12898567
A single nucleotide polymorphism (TNF(-308A)) within the promoter region of the gene encoding tumor necrosis factor (TNF), has been significantly associated with schizophrenia in a study of Italian patients and...