Deepak Ramanujam
Overview
Explore the profile of Deepak Ramanujam including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
23
Citations
1011
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Sultan I, Ramste M, Peletier P, Hemanthakumar K, Ramanujam D, Tirronen A, et al.
Circ Res
. 2024 Apr;
134(11):1465-1482.
PMID: 38655691
Background: Preclinical studies have shown the therapeutic potential of VEGF-B (vascular endothelial growth factor B) in revascularization of the ischemic myocardium, but the associated cardiac hypertrophy and adverse side effects...
2.
Beck C, Ramanujam D, Vaccarello P, Widenmeyer F, Feuerherd M, Cheng C, et al.
Nat Commun
. 2023 Jul;
14(1):4564.
PMID: 37507393
Recent studies of severe acute inflammatory lung disease including COVID-19 identify macrophages to drive pulmonary hyperinflammation and long-term damage such as fibrosis. Here, we report on the development of a...
3.
Kaltenbacher T, Loprich J, Maresch R, Weber J, Muller S, Oellinger R, et al.
Nat Protoc
. 2022 Mar;
17(4):1142-1188.
PMID: 35288718
Genetically engineered mouse models (GEMMs) transformed the study of organismal disease phenotypes but are limited by their lengthy generation in embryonic stem cells. Here, we describe methods for rapid and...
4.
Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing
Kogan P, Wirth F, Tomar A, Darr J, Teperino R, Lahm H, et al.
Basic Res Cardiol
. 2022 Mar;
117(1):11.
PMID: 35258704
Cardiosphere-derived cells (CDCs) generated from human cardiac biopsies have been shown to have disease-modifying bioactivity in clinical trials. Paradoxically, CDCs' cellular origin in the heart remains elusive. We studied the...
5.
Esfandyari D, Idrissou B, Hennis K, Avramopoulos P, Dueck A, El-Battrawy I, et al.
Nat Commun
. 2022 Jan;
13(1):220.
PMID: 35017523
Abnormalities of ventricular action potential cause malignant cardiac arrhythmias and sudden cardiac death. Here, we aim to identify microRNAs that regulate the human cardiac action potential and ask whether their...
6.
Hoepfner J, Leonardy J, Lu D, Schmidt K, Hunkler H, Biss S, et al.
Mol Ther
. 2021 Dec;
30(3):1265-1274.
PMID: 34856383
Physiological and pathological cardiovascular processes are tightly regulated by several cellular mechanisms. Non-coding RNAs, including long non-coding RNAs (lncRNAs), represent one important class of molecules involved in regulatory processes within...
7.
Ramanujam D, Schon A, Beck C, Vaccarello P, Felician G, Dueck A, et al.
Circulation
. 2021 Feb;
143(15):1513-1525.
PMID: 33550817
Background: Cardiac macrophages (cMPs) are increasingly recognized as important regulators of myocardial homeostasis and disease, yet the role of noncoding RNA in these cells is largely unknown. Small RNA sequencing...
8.
Merl-Pham J, Basak T, Knuppel L, Ramanujam D, Athanason M, Behr J, et al.
Matrix Biol Plus
. 2021 Feb;
1:100005.
PMID: 33543004
Lung fibrosis is characterized by excessive deposition of extracellular matrix (ECM), in particular collagens, by fibroblasts in the interstitium. Transforming growth factor-β1 (TGF-β1) alters the expression of many extracellular matrix...
9.
Anger M, Scheufele F, Ramanujam D, Meyer K, Nakajima H, Field L, et al.
PLoS One
. 2020 Dec;
15(12):e0244096.
PMID: 33351822
Fibrosis is a pathognomonic feature of structural heart disease and counteracted by distinct cardioprotective mechanisms, e.g. activation of the phosphoinositide 3-kinase (PI3K) / AKT pro-survival pathway. The Cullin-RING E3 ubiquitin...
10.
Kanoldt V, Kluger C, Barz C, Schweizer A, Ramanujam D, Windgasse L, et al.
Nat Commun
. 2020 Dec;
11(1):6403.
PMID: 33335089
Vinculin is a ubiquitously expressed protein, crucial for the regulation of force transduction in cells. Muscle cells express a vinculin splice-isoform called metavinculin, which has been associated with cardiomyopathies. However,...