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Deendayal Mandal

Explore the profile of Deendayal Mandal including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 584
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Recent Articles
1.
Rafinejad A, Fallah-Tafti A, Tiwari R, Nasrolahi Shirazi A, Mandal D, Shafiee A, et al.
Daru . 2013 Jan; 20(1):100. PMID: 23351304
Background: A series of 2-amino-4-aryl-4H-benzo[h or f]chromene-3-carbonitrile derivatives were synthesized and evaluated for inhibition of Src kinase and cell proliferation in breast carcinoma (BT-20) cell lines. Methods: The one-pot, three-component...
2.
Sharma R, Singh S, Tiwari R, Mandal D, Olsen C, Parmar V, et al.
Bioorg Med Chem . 2012 Oct; 20(23):6821-30. PMID: 23098606
A series of peracetylated O-aryl α,β-d-ribofuranosides have been synthesized and an efficient biocatalytic methodology has been developed for the separation of their anomers which was otherwise almost impossible by column...
3.
Chhikara B, Mandal D, Parang K
J Med Chem . 2012 Jan; 55(4):1500-10. PMID: 22276998
A number of lipophilic 14-substituted derivatives of doxorubicin were synthesized through conjugation of doxorubicin-14-hemisuccinate with different fatty amines or tetradecanol to enhance the lipophilicity, cellular uptake, and cellular retention for...
4.
Mandal D, Nasrolahi Shirazi A, Parang K
Angew Chem Int Ed Engl . 2011 Sep; 50(41):9633-7. PMID: 21919161
No abstract available.
5.
Fallah-Tafti A, Tiwari R, Nasrolahi Shirazi A, Akbarzadeh T, Mandal D, Shafiee A, et al.
Med Chem . 2011 Aug; 7(5):466-72. PMID: 21801146
Src kinase mutations and/or overexpression have been implicated in the development of a number of human cancer including colon, breast, and lung cancers. Thus, designing potent and selective Src kinase...
6.
Chhikara B, St Jean N, Mandal D, Kumar A, Parang K
Eur J Med Chem . 2011 Mar; 46(6):2037-42. PMID: 21420207
Doxorubicin is extensively used in anticancer therapy. Doxorubicin is highly hydrophilic, has short half-life, and its use is associated with severe side effects at high doses. Fatty acyl amide derivatives...
7.
Gupta A, Mandal D, Ahmadibeni Y, Parang K, Bothun G
Eur Biophys J . 2011 Mar; 40(6):727-36. PMID: 21409455
Short cationic linear peptide analogs (LPAs, prepared as Arg-C( n )-Arg-C( n )-Lys, where C( n ) represents an alkyl linkage with n = 4, 7 or 11) were synthesized...
8.
Agarwal H, Loethan K, Mandal D, Doncel G, Parang K
Bioorg Med Chem Lett . 2011 Mar; 21(7):1917-21. PMID: 21382714
A number of 5'-O-fatty acyl derivatives of 2',3'-didehydro-2',3'-dideoxythymidine (stavudine, d4T) were synthesized and evaluated for anti-HIV activities against cell-free and cell-associated virus, cellular cytotoxicity, and cellular uptake studies. The conjugates...
9.
Kumar A, Ahmad I, Chhikara B, Tiwari R, Mandal D, Parang K
Bioorg Med Chem Lett . 2011 Feb; 21(5):1342-6. PMID: 21300544
A series of two classes of 3-phenylpyrazolopyrimidine-1,2,3-triazole conjugates were synthesized using click chemistry approach. All compounds were evaluated for inhibition of Src kinase and human ovarian adenocarcinoma (SK-Ov-3), breast carcinoma...
10.
Kumar D, Reddy V, Kumar A, Mandal D, Tiwari R, Parang K
Bioorg Med Chem Lett . 2010 Nov; 21(1):449-52. PMID: 21084189
Two classes of 1,4-disubstituted 1,2,3-triazoles were synthesized using one-pot reaction of α-tosyloxy ketones/α-halo ketones, sodium azide, and terminal alkynes in the presence of aq PEG (1:1, v/v) using the click...