Declan Bennett
Overview
Explore the profile of Declan Bennett including associated specialties, affiliations and a list of published articles.
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4
Citations
22
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Recent Articles
1.
Liu X, Chapple R, Bennett D, Wright W, Sanjali A, Culp E, et al.
Cell Genom
. 2025 Jan;
5(1):100739.
PMID: 39788105
Exploratory analysis of single-cell RNA sequencing (scRNA-seq) typically relies on hard clustering over two-dimensional projections like uniform manifold approximation and projection (UMAP). However, such methods can severely distort the data...
2.
Nembaware V, Bennett D, Chimusa E, Chikowore T, Daodu R, Bitoungui V, et al.
Trends Genet
. 2023 Sep;
39(11):803-807.
PMID: 37714735
To accelerate the impact of African genomics on human health, data science skills and awareness of Africa's rich genetic diversity must be strengthened globally. We describe the first African genomics...
3.
Goder A, Quinlan A, Rainey M, Bennett D, Shamavu D, Corso J, et al.
iScience
. 2023 Jun;
26(6):106951.
PMID: 37378325
CDC7 kinase is crucial for DNA replication initiation and fork processing. CDC7 inhibition mildly activates the ATR pathway, which further limits origin firing; however, to date the relationship between CDC7...
4.
Bennett D, OShea D, Ferguson J, Morris D, Seoighe C
Sci Rep
. 2021 Oct;
11(1):19571.
PMID: 34599249
Ongoing increases in the size of human genotype and phenotype collections offer the promise of improved understanding of the genetics of complex diseases. In addition to the biological insights that...
5.
Rainey M, Bennett D, ODea R, Zanchetta M, Voisin M, Seoighe C, et al.
Cell Rep
. 2020 Sep;
32(9):108096.
PMID: 32877678
DNA replication initiates from multiple origins, and selective CDC7 kinase inhibitors (CDC7is) restrain cell proliferation by limiting origin firing. We have performed a CRISPR-Cas9 genome-wide screen to identify genes that,...