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Scott M Williams

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Articles 265
Citations 7614
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Recent Articles
1.
Riglea T, Dessy T, Kalubi J, Goulet D, Ikwa Ndol Mbutiwi F, Williams S, et al.
J Hum Hypertens . 2025 Mar; PMID: 40089570
Genome-wide association studies (GWAS) in adults have identified single nucleotide polymorphisms (SNPs) associated with systolic blood pressure (SBP), but it is unclear whether the findings apply in youth. Further, the...
2.
Ciesielski T, Tosto G, Durodoye R, Rajabali F, Akinyemi R, Byrd G, et al.
medRxiv . 2024 Aug; PMID: 39148832
Introduction: Clinical and genetic studies have implicated lipid dysfunction in Alzheimer Disease (AD) pathogenesis. However, lipid consumption at the individual-level does not vary greatly within most cohorts, and multiple lipids...
3.
Hannon E, Marsit C, Dent A, Embury P, Ogolla S, Midem D, et al.
BioData Min . 2024 Jul; 17(1):21. PMID: 38992677
Background: Changing cell-type proportions can confound studies of differential gene expression or DNA methylation (DNAm) from peripheral blood mononuclear cells (PBMCs). We examined how cell-type proportions derived from the transcriptome...
4.
Hannon E, Marsit C, Dent A, Embury P, Ogolla S, Midem D, et al.
Res Sq . 2024 Apr; PMID: 38645047
Background: Changing cell-type proportions can confound studies of differential gene expression or DNA methylation (DNAm) from peripheral blood mononuclear cells (PBMCs). We examined how cell-type proportions derived from the transcriptome...
5.
Verma S, Gudiseva H, Chavali V, Salowe R, Bradford Y, Guare L, et al.
Cell . 2024 Jan; 187(2):464-480.e10. PMID: 38242088
Primary open-angle glaucoma (POAG), the leading cause of irreversible blindness worldwide, disproportionately affects individuals of African ancestry. We conducted a genome-wide association study (GWAS) for POAG in 11,275 individuals of...
6.
Ciesielski T, Sirugo G, Iyengar S, Williams S
NPJ Genom Med . 2024 Jan; 9(1):3. PMID: 38195641
No abstract available.
7.
Rifkin S, Miller A, Montalvan-Sanchez E, Norwood D, Martinez E, Waterboer T, et al.
Sci Rep . 2023 Oct; 13(1):16515. PMID: 37783717
Biomass cookstove food preparation is linked to aero-digestive cancers, mediated by ingested and inhaled carcinogens (e.g., heterocyclic amines, and polycyclic aromatic hydrocarbons). We investigated the association between gastric adenocarcinoma, wood...
8.
Nembaware V, Bennett D, Chimusa E, Chikowore T, Daodu R, Bitoungui V, et al.
Trends Genet . 2023 Sep; 39(11):803-807. PMID: 37714735
To accelerate the impact of African genomics on human health, data science skills and awareness of Africa's rich genetic diversity must be strengthened globally. We describe the first African genomics...
9.
Cramer E, Bartlett J, Chan E, Gaedigk A, Ratsimbasoa A, Mehlotra R, et al.
Pharmacogenomics . 2023 Aug; 24(11):583-597. PMID: 37551613
Antimalarial primaquine (PQ) eliminates liver hypnozoites of   gene variation contributes to PQ therapeutic failure. Additional gene variation may contribute to PQ efficacy. Information on pharmacogenomic variation in Madagascar, with malaria...
10.
Mead E, Wang C, Phung J, Fu J, Williams S, Merialdi M, et al.
Reprod Sci . 2023 Jul; 30(12):3410-3427. PMID: 37450251
Preterm birth (PTB), defined as the birth of a child before 37 completed weeks gestation, affects approximately 11% of live births and is the leading cause of death in children...