Debashree Basudhar
Overview
Explore the profile of Debashree Basudhar including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
450
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0
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Recent Articles
1.
Ridnour L, Cheng R, Kedei N, Somasundaram V, Bhattacharyya D, Basudhar D, et al.
JCI Insight
. 2024 Jun;
9(12).
PMID: 38912586
Immune therapy is the new frontier of cancer treatment. Therapeutic radiation is a known inducer of immune response and can be limited by immunosuppressive mediators including cyclooxygenase-2 (COX2) that is...
2.
Cheng R, Patel N, Back T, Basudhar D, Somasundaram V, Kalen J, et al.
J Vis Exp
. 2020 Apr;
(157).
PMID: 32250353
Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited therapeutic options. When compared to patients with less aggressive breast tumors, the 5-year survival rate of TNBC patients...
3.
Somasundaram V, Gilmore A, Basudhar D, Palmieri E, Scheiblin D, Heinz W, et al.
Redox Biol
. 2019 Nov;
28:101354.
PMID: 31683257
The role of nitric oxide (NO) in cancer progression has largely been studied in the context of tumor NOS2 expression. However, pro- versus anti-tumor signaling is also affected by tumor...
4.
Fujita M, Somasundaram V, Basudhar D, Cheng R, Ridnour L, Higuchi H, et al.
Redox Biol
. 2019 Mar;
22:101158.
PMID: 30852389
Pancreatic cancer is a highly metastatic tumor with an extremely low 5-year survival rate. Lack of efficient diagnostics and dearth of effective therapeutics that can target the cancer as well...
5.
Basudhar D, Bharadwaj G, Somasundaram V, Cheng R, Ridnour L, Fujita M, et al.
Br J Pharmacol
. 2018 Aug;
176(2):155-176.
PMID: 30152521
Recent findings suggest that co-expression of NOS2 and COX2 is a strong prognostic indicator in triple-negative breast cancer patients. These two key inflammation-associated enzymes are responsible for the biosynthesis of...
6.
Somasundaram V, Basudhar D, Bharadwaj G, No J, Ridnour L, Cheng R, et al.
Antioxid Redox Signal
. 2018 Apr;
30(8):1124-1143.
PMID: 29634348
Significance: Cancer is a complex disease, which not only involves the tumor but its microenvironment comprising different immune cells as well. Nitric oxide (NO) plays specific roles within tumor cells...
7.
Basudhar D, Glynn S, Greer M, Somasundaram V, No J, Scheiblin D, et al.
Proc Natl Acad Sci U S A
. 2017 Nov;
114(49):13030-13035.
PMID: 29087320
Proinflammatory signaling pathways are commonly up-regulated in breast cancer. In estrogen receptor-negative (ER) and triple-negative breast cancer (TNBC), nitric oxide synthase-2 (NOS2) and cyclooxygenase-2 (COX2) have been described as independent...
8.
de Oliveira G, Cheng R, Ridnour L, Basudhar D, Somasundaram V, McVicar D, et al.
Antioxid Redox Signal
. 2016 Aug;
26(18):1059-1077.
PMID: 27494631
Significance: Gastrointestinal (GI) cancer taken together constitutes one of the most common cancers worldwide with a broad range of etiological mechanisms. In this review, we have examined the impact of...
9.
Basudhar D, Somasundaram V, de Oliveira G, Kesarwala A, Heinecke J, Cheng R, et al.
Antioxid Redox Signal
. 2016 Jul;
26(18):1044-1058.
PMID: 27464521
Significance: Breast cancer is the second leading cause of cancer-related deaths among women in the United States. Development and progression of malignancy are associated with diverse cell signaling pathways that...
10.
Basudhar D, Madrona Y, Yukl E, Sivaramakrishnan S, Nishida C, Moenne-Loccoz P, et al.
J Biol Chem
. 2016 May;
291(31):16100-11.
PMID: 27235395
Mycobacterium tuberculosis DosS is critical for the induction of M. tuberculosis dormancy genes in response to nitric oxide (NO), carbon monoxide (CO), or hypoxia. These environmental stimuli, which are sensed...