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Dean Yimlamai

Explore the profile of Dean Yimlamai including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1996
Followers 0
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Recent Articles
1.
Sakuma I, Gaspar R, Nasiri A, Dufour S, Kahn M, Zheng J, et al.
bioRxiv . 2025 Mar; PMID: 40060523
Significance Statement: Metabolic dysfunction-associated steatohepatitis (MASH) is a progressive liver disease linked to fibrosis. The role of specific lipid species in its pathogenesis remains debated. Using dietary, molecular, and genetic...
2.
Mooring M, Yeung G, Luukkonen P, Liu S, Akbar M, Zhang G, et al.
Sci Transl Med . 2023 Sep; 15(715):eade3157. PMID: 37756381
Obesity is increasing worldwide and leads to a multitude of metabolic diseases, including cardiovascular disease, type 2 diabetes, nonalcoholic fatty liver disease, and nonalcoholic steatohepatitis (NASH). Cysteine-rich angiogenic inducer 61...
3.
Lin Y, Zeng Q, Jia Y, Wang Z, Li L, Hsieh M, et al.
Hepatology . 2023 Apr; 78(4):1133-1148. PMID: 37039560
Background And Aims: The liver is remarkably regenerative and can completely recover even when 80% of its mass is surgically removed. Identification of secreted factors that regulate liver growth would...
4.
Luukkonen P, Sakuma I, Gaspar R, Mooring M, Nasiri A, Kahn M, et al.
Proc Natl Acad Sci U S A . 2023 Jan; 120(4):e2217543120. PMID: 36669104
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, in which prognosis is determined by liver fibrosis. A common variant in hydroxysteroid 17-beta dehydrogenase 13 (, rs72613567-A)...
5.
Yao K, Tarabra E, Sia D, Morotti R, Fawaz R, Valentino P, et al.
Hepatol Commun . 2022 Mar; 6(7):1598-1610. PMID: 35312185
Nonalcoholic fatty liver disease (NAFLD) is the most common type of chronic liver disease in children. The mechanisms that drive NAFLD disease progression in this specific patient population remain poorly...
6.
Toothaker J, Olaloye O, McCourt B, McCourt C, Silva T, Case R, et al.
Development . 2022 Jan; 149(8). PMID: 35050308
Maintenance of a healthy pregnancy is reliant on a successful balance between the fetal and maternal immune systems. Although the maternal mechanisms responsible have been well studied, those used by...
7.
Chen A, Jiang Y, Li Z, Wu L, Santiago U, Zou H, et al.
J Clin Invest . 2021 Jul; 131(16). PMID: 34228644
No abstract available.
8.
Airik M, Schuler M, McCourt B, Weiss A, Herdman N, Ludtke T, et al.
Hum Mol Genet . 2020 Sep; 29(18):3064-3080. PMID: 32886109
ANKS6 is a ciliary protein that localizes to the proximal compartment of the primary cilium, where it regulates signaling. Mutations in the ANKS6 gene cause multiorgan ciliopathies in humans, which...
9.
Alsamman S, Christenson S, Yu A, Ayad N, Mooring M, Segal J, et al.
Sci Transl Med . 2020 Aug; 12(557). PMID: 32817366
Hepatic stellate cells (HSCs) drive hepatic fibrosis. Therapies that inactivate HSCs have clinical potential as antifibrotic agents. We previously identified acid ceramidase (aCDase) as an antifibrotic target. We showed that...
10.
Zhang Y, Guillermier C, De Raedt T, Cox A, Maertens O, Yimlamai D, et al.
iScience . 2020 Jul; 23(8):101355. PMID: 32712466
Malignant tumors exhibit high degrees of genomic heterogeneity at the cellular level, leading to the view that subpopulations of tumor cells drive growth and treatment resistance. To examine the degree...