David Tannahill
Overview
Explore the profile of David Tannahill including associated specialties, affiliations and a list of published articles.
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48
Citations
4158
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Recent Articles
1.
Flynn S, Dhir S, Herka K, Doyle C, Melidis L, Simeone A, et al.
Genome Biol
. 2024 Sep;
25(1):237.
PMID: 39227991
Methods to measure chromatin contacts at genomic regions bound by histone modifications or proteins are important tools to investigate chromatin organization. However, such methods do not capture the possible involvement...
2.
Chen Y, Simeone A, Melidis L, Martinez Cuesta S, Tannahill D, Balasubramanian S
ACS Chem Biol
. 2024 Feb;
19(3):736-742.
PMID: 38417105
Four-stranded G-quadruplexes (G4s) are DNA secondary structures that can form in the human genome. G4 structures have been detected in gene promoters and are associated with transcriptionally active chromatin and...
3.
Esain-Garcia I, Kirchner A, Melidis L, Araujo Tavares R, Dhir S, Simeone A, et al.
Proc Natl Acad Sci U S A
. 2024 Feb;
121(7):e2320240121.
PMID: 38315865
DNA structure can regulate genome function. Four-stranded DNA G-quadruplex (G4) structures have been implicated in transcriptional regulation; however, previous studies have not directly addressed the role of an individual G4...
4.
Galli S, Melidis L, Flynn S, Varshney D, Simeone A, Spiegel J, et al.
J Am Chem Soc
. 2022 Dec;
144(50):23096-23103.
PMID: 36488193
G-quadruplexes (G4s) are four-stranded DNA secondary structures that occur in the human genome and play key roles in transcription, replication, and genome stability. G4-specific molecular probes are of vital importance...
5.
Hui W, Simeone A, Zyner K, Tannahill D, Balasubramanian S
Sci Rep
. 2022 Jan;
12(1):908.
PMID: 35022562
No abstract available.
6.
Zyner K, Simeone A, Flynn S, Doyle C, Marsico G, Adhikari S, et al.
Nat Commun
. 2022 Jan;
13(1):142.
PMID: 35013231
The establishment of cell identity during embryonic development involves the activation of specific gene expression programmes and is underpinned by epigenetic factors including DNA methylation and histone post-translational modifications. G-quadruplexes...
7.
Hui W, Simeone A, Zyner K, Tannahill D, Balasubramanian S
Sci Rep
. 2021 Dec;
11(1):23641.
PMID: 34880271
G-quadruplexes (G4s) are four-stranded DNA secondary structures that form in guanine-rich regions of the genome. G4s have important roles in transcription and replication and have been implicated in genome instability...
8.
Varshney D, Martinez Cuesta S, Herdy B, Abdullah U, Tannahill D, Balasubramanian S
Sci Rep
. 2021 Nov;
11(1):22735.
PMID: 34815422
Four-stranded G-quadruplex (G4) structures form from guanine-rich tracts, but the extent of their formation in cellular RNA and details of their role in RNA biology remain poorly defined. Herein, we...
9.
Shen J, Varshney D, Simeone A, Zhang X, Adhikari S, Tannahill D, et al.
Genome Biol
. 2021 May;
22(1):143.
PMID: 33962653
Background: Four-stranded G-quadruplexes (G4s) are DNA secondary structures in the human genome that are primarily found in active promoters associated with elevated transcription. Here, we explore the relationship between the...
10.
Spiegel J, Martinez Cuesta S, Adhikari S, Hansel-Hertsch R, Tannahill D, Balasubramanian S
Genome Biol
. 2021 Apr;
22(1):117.
PMID: 33892767
Background: The binding of transcription factors (TF) to genomic targets is critical in the regulation of gene expression. Short, double-stranded DNA sequence motifs are routinely implicated in TF recruitment, but...