David Stroebel
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Explore the profile of David Stroebel including associated specialties, affiliations and a list of published articles.
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31
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948
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Recent Articles
11.
Fiorucci A, Bourbousse C, Concia L, Rougee M, Deton-Cabanillas A, Zabulon G, et al.
Genome Biol
. 2019 May;
20(1):100.
PMID: 31113491
Background: The functional determinants of H3K4me3, their potential dependency on histone H2B monoubiquitination, and their contribution to defining transcriptional regimes are poorly defined in plant systems. Unlike in Saccharomyces cerevisiae,...
12.
Esmenjaud J, Stroebel D, Chan K, Grand T, David M, Wollmuth L, et al.
EMBO J
. 2018 Nov;
38(2).
PMID: 30396997
NMDA receptors (NMDARs) are glutamate-gated ion channels that are key mediators of excitatory neurotransmission and synaptic plasticity throughout the central nervous system. They form massive heterotetrameric complexes endowed with unique...
13.
Nassrallah A, Rougee M, Bourbousse C, Drevensek S, Fonseca S, Iniesto E, et al.
Elife
. 2018 Sep;
7.
PMID: 30192741
DE-ETIOLATED 1 (DET1) is an evolutionarily conserved component of the ubiquitination machinery that mediates the destabilization of key regulators of cell differentiation and proliferation in multicellular organisms. In this study,...
14.
Stroebel D, Casado M, Paoletti P
Curr Opin Physiol
. 2018 Apr;
2:1-12.
PMID: 29682629
N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels that play crucial roles in brain development and synaptic plasticity. They are also therapeutic targets of interest since their dysfunction is associated with...
15.
Yu I, Planelles-Herrero V, Sourigues Y, Moussaoui D, Sirkia H, Kikuti C, et al.
Nat Commun
. 2017 Jun;
8:15864.
PMID: 28660889
Cadherin linkages between adjacent stereocilia and microvilli are essential for mechanotransduction and maintaining their organization. They are anchored to actin through interaction of their cytoplasmic domains with related tripartite complexes...
16.
Fremont S, Hammich H, Bai J, Wioland H, Klinkert K, Rocancourt M, et al.
Nat Commun
. 2017 Feb;
8:14528.
PMID: 28230050
Cytokinetic abscission, the terminal step of cell division, crucially depends on the local constriction of ESCRT-III helices after cytoskeleton disassembly. While the microtubules of the intercellular bridge are cut by...
17.
Fossati M, Pizzarelli R, Schmidt E, Kupferman J, Stroebel D, Polleux F, et al.
Neuron
. 2016 Jul;
91(2):356-69.
PMID: 27373832
The proper function of neural circuits requires spatially and temporally balanced development of excitatory and inhibitory synapses. However, the molecular mechanisms coordinating excitatory and inhibitory synaptogenesis remain unknown. Here we...
18.
Stroebel D, Buhl D, Knafels J, Chanda P, Green M, Sciabola S, et al.
Mol Pharmacol
. 2016 Feb;
89(5):541-51.
PMID: 26912815
N-methyl-d-aspartate receptors (NMDARs) are glutamate-gated ion channels that play key roles in brain physiology and pathology. Because numerous pathologic conditions involve NMDAR overactivation, subunit-selective antagonists hold strong therapeutic potential, although...
19.
Stroebel D, Carvalho S, Grand T, Zhu S, Paoletti P
J Neurosci
. 2014 Dec;
34(50):16630-6.
PMID: 25505316
Ligand-gated ion channels (LGICs) mediate fast synaptic transmission in the CNS. Typically, these membrane proteins are multimeric complexes associating several homologous subunits around a central pore. Because of the large...
20.