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David Stroebel

Explore the profile of David Stroebel including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 948
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Recent Articles
1.
Rocher C, Vernale A, Fierro-Constain L, Sejourne N, Chenesseau S, Marschal C, et al.
J Exp Zool B Mol Dev Evol . 2024 Oct; 342(8):503-528. PMID: 39364688
The comparative study of the four non-bilaterian phyla (Cnidaria, Placozoa, Ctenophora, and Porifera) provides insights into the origin of bilaterian traits. To complete our knowledge of the cell biology and...
2.
Piot L, Heroven C, Bossi S, Zamith J, Malinauskas T, Johnson C, et al.
Science . 2023 Dec; 382(6677):1389-1394. PMID: 38060673
Fast synaptic neurotransmission in the vertebrate central nervous system relies primarily on ionotropic glutamate receptors (iGluRs), which drive neuronal excitation, and type A γ-aminobutyric acid receptors (GABARs), which are responsible...
3.
Bricout R, Weil D, Stroebel D, Genovesio A, Crollius H
Mol Biol Evol . 2023 Mar; 40(3). PMID: 36857092
Amino acids evolve at different speeds within protein sequences, because their functional and structural roles are different. Notably, amino acids located at the surface of proteins are known to evolve...
4.
Tian M, Stroebel D, Piot L, David M, Ye S, Paoletti P
Nat Commun . 2021 Aug; 12(1):4709. PMID: 34354080
Allostery represents a fundamental mechanism of biological regulation that involves long-range communication between distant protein sites. It also provides a powerful framework for novel therapeutics. NMDA receptors (NMDARs), glutamate-gated ionotropic...
5.
Wang H, Lv S, Stroebel D, Zhang J, Pan Y, Huang X, et al.
Neuron . 2021 Jun; 109(15):2443-2456.e5. PMID: 34186027
N-methyl-D-aspartate (NMDA) receptors are glutamate-gated calcium-permeable ion channels that are widely implicated in synaptic transmission and plasticity. Here, we report a gallery of cryo-electron microscopy (cryo-EM) structures of the human...
6.
Stroebel D, Mony L, Paoletti P
Neuropharmacology . 2021 May; 193:108631. PMID: 34058193
Ionotropic glutamate receptors (iGluRs) are ligand-gated ion channels that mediate the majority of excitatory neurotransmission in the vertebrate CNS. Classified as AMPA, kainate, delta and NMDA receptors, iGluRs are central...
7.
Velours C, Aumont-Nicaise M, Uebel S, England P, Velazquez-Campoy A, Stroebel D, et al.
Eur Biophys J . 2021 Apr; 50(3-4):331. PMID: 33904993
No abstract available.
8.
Velours C, Aumont-Nicaise M, Uebel S, England P, Velazquez-Campoy A, Stroebel D, et al.
Eur Biophys J . 2021 Apr; 50(3-4):313-330. PMID: 33792745
Biophysical quantification of protein interactions is central to unveil the molecular mechanisms of cellular processes. Researchers can choose from a wide panel of biophysical methods that quantify molecular interactions in...
9.
Mony L, Stroebel D, Isacoff E
Proc Natl Acad Sci U S A . 2020 Aug; 117(34):20898-20907. PMID: 32788354
The voltage-gated proton channel Hv1 is a member of the voltage-gated ion channel superfamily, which stands out in design: It is a dimer of two voltage-sensing domains (VSDs), each containing...
10.
Stroebel D, Paoletti P
J Physiol . 2020 Aug; 599(10):2615-2638. PMID: 32786006
Ionotropic glutamate receptors (iGluRs) are a major class of ligand-gated ion channels that are widespread in the living kingdom. Their critical role in excitatory neurotransmission and brain function of arthropods...