David Shugar
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Explore the profile of David Shugar including associated specialties, affiliations and a list of published articles.
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42
Citations
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Recent Articles
21.
Qin X, Kwansa H, Bucci E, Dore S, Boehning D, Shugar D, et al.
Am J Physiol Regul Integr Comp Physiol
. 2008 May;
295(2):R498-504.
PMID: 18495834
Carbon monoxide derived from heme oxygenase (HO) may participate in cerebrovascular regulation under specific circumstances. Previous work has shown that HO contributes to feline pial arteriolar dilation to acetylcholine after...
22.
Wierzchowski J, Iwanska B, Bzowska A, Shugar D
Nucleosides Nucleotides Nucleic Acids
. 2007 Dec;
26(6-7):849-54.
PMID: 18066912
Phosphorolysis of 7-methylguanosine by calf spleen purine nucleoside phosphorylase (PNP) is weakly inhibited, uncompetitively, by Formycin B (FB) with Ki = 100 micro M and more effectively by its aglycone...
23.
24.
Modrak-Wojcik A, Kirilenko A, Shugar D, Kierdaszuk B
Eur Biophys J
. 2007 Jul;
37(2):153-64.
PMID: 17639373
Kinetics of the reactions of purine nucleoside phosphorylases (PNP) from E. coli (PNP-I, the product of the deoD gene) and human erythrocytes with their natural substrates guanosine (Guo), inosine (Ino),...
25.
Poznanski J, Najda A, Bretner M, Shugar D
J Phys Chem A
. 2007 Jun;
111(28):6501-9.
PMID: 17585743
The prototropic tautomerism in anhydrous DMSO of benzotriazole and six derivatives symmetrically substituted on the benzene ring (5,6-dichloro, tetrachloro, 4,7-dibromo, tetrabromo, 5,6-dimethyl, and tetramethyl), was followed by both experimental (13C...
26.
Pi J, Bai Y, Reece J, Williams J, Liu D, Freeman M, et al.
Free Radic Biol Med
. 2007 May;
42(12):1797-806.
PMID: 17512459
Nrf2 is a key transcription factor in the cellular response to oxidative stress. In this study we identify two phosphorylated forms of endogenous human Nrf2 after chemically induced oxidative stress...
27.
Focher F, Lossani A, Verri A, Spadari S, Maioli A, Gambino J, et al.
Antimicrob Agents Chemother
. 2007 Apr;
51(6):2028-34.
PMID: 17438061
Herpes B virus (B virus [BV]) is a macaque herpesvirus that is occasionally transmitted to humans where it can cause rapidly ascending encephalitis that is often fatal. To understand the...
28.
Wierzchowski J, Stepniak K, Bzowska A, Shugar D
Nucleosides Nucleotides Nucleic Acids
. 2005 Oct;
24(5-7):459-64.
PMID: 16247971
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, an excellent fluorescent/fluorogenic substrate for the synthetic pathway of the reaction, and its 9-(2-phosphonylmethoxyethyl) derivative, a...
29.
Zien P, Duncan J, Skierski J, Bretner M, Litchfield D, Shugar D
Biochim Biophys Acta
. 2005 Oct;
1754(1-2):271-80.
PMID: 16203192
The development of selective cell-permeable inhibitors of protein kinase CK2 has represented an important advance in the field. However, it is important to not overlook the existence of discrete molecular...
30.
Mesquita R, Oliveira F, Shugar D, Fantappie M, Silva-Neto M
Biochem Biophys Res Commun
. 2005 Aug;
335(3):690-9.
PMID: 16099432
Rhodnius prolixus is a blood-sucking bug whose saliva contains a family of nitric oxide-carrying proteins named nitrophorins (NPs). Saliva is injected into the host bloodstream during insect feeding. Nitric oxide...