David Ruff
Overview
Explore the profile of David Ruff including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
197
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0
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Recent Articles
1.
Demaree B, Delley C, Vasudevan H, Peretz C, Ruff D, Smith C, et al.
Nat Commun
. 2021 Mar;
12(1):1583.
PMID: 33707421
Studies of acute myeloid leukemia rely on DNA sequencing and immunophenotyping by flow cytometry as primary tools for disease characterization. However, leukemia tumor heterogeneity complicates integration of DNA variants and...
2.
Ten Hacken E, Clement K, Li S, Hernandez-Sanchez M, Redd R, Wang S, et al.
Genome Biol
. 2020 Oct;
21(1):266.
PMID: 33081820
CRISPR-Cas9 gene editing has transformed our ability to rapidly interrogate the functional impact of somatic mutations in human cancers. Droplet-based technology enables the analysis of Cas9-introduced gene edits in thousands...
3.
Piccoli G, Giuva D, Ruff D, Genovese P, Apicella M, Kuprina N, et al.
Nephrol Dial Transplant
. 2016 Sep;
31(12):2019-2022.
PMID: 27651469
No abstract available.
4.
Ruff D, Giuva D, Finnel S, Cattaneo G, Ronco R, Kourilsky O, et al.
Nephrol Dial Transplant
. 2016 Jul;
31(11):1822-1825.
PMID: 27474748
No abstract available.
5.
Greenwood C, Ruff D, Kirvell S, Johnson G, Dhillon H, Bustin S
Biomol Detect Quantif
. 2016 Apr;
4:10-6.
PMID: 27077033
Proximity assays are immunohistochemical tools that utilise two or more DNA-tagged aptamers or antibodies binding in close proximity to the same protein or protein complex. Amplification by PCR or isothermal...
6.
Stahlberg A, Gustafsson C, Engtrom K, Thomsen C, Dolatabadi S, Jonasson E, et al.
PLoS One
. 2014 Nov;
9(11):e113110.
PMID: 25393000
Myxoid/round-cell liposarcoma (MLS/RCLS) is characterized by either the fusion gene FUS-DDIT3 or the less commonly occurring EWSR1-DDIT3 and most cases carry few or no additional cytogenetic changes. There are conflicting...
7.
Bandla S, Peters J, Ruff D, Chen S, Li C, Song K, et al.
Ann Surg
. 2014 Feb;
260(1):72-80.
PMID: 24509200
Objective: To determine and compare the frequency of cancer-associated genetic abnormalities in esophageal metaplasia biopsies with and without goblet cells. Background: Barrett's esophagus is associated with increased risk of esophageal...
8.
Ruff D, Lieu P
Methods Mol Biol
. 2013 Apr;
997:225-36.
PMID: 23546760
Reprogramming human somatic cells to induced pluripotent stem cells is an important avenue in biological research. Advances in the profiling of human stem cells have identified important pluripotency maintenance factors....
9.
Stahlberg A, Thomsen C, Ruff D, Aman P
Clin Chem
. 2012 Sep;
58(12):1682-91.
PMID: 23014600
Background: The single cell represents the basic unit of all organisms. Most investigations have been performed on large cell populations, but understanding cell dynamics and heterogeneity requires single-cell analysis. Current...
10.
Ruff D, MacArthur C, Tran H, Bergseid J, Tian J, Shannon M, et al.
Stem Cells Dev
. 2011 Apr;
21(4):530-8.
PMID: 21476854
The capability to reprogram human somatic cells to induced pluripotent stem cells (iPSCs) has opened a new area of biology and provides unprecedented access to patient-specific iPSCs for drug screening,...