David R Martinez
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Explore the profile of David R Martinez including associated specialties, affiliations and a list of published articles.
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Articles
117
Citations
10623
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Recent Articles
1.
Seo J, Polster J, Israelow B, Corbett-Helaire K, Martinez D
Nat Biotechnol
. 2024 Dec;
42(12):1765-1767.
PMID: 39643701
No abstract available.
2.
Suryadevara N, Kose N, Bangaru S, Binshtein E, Munt J, Martinez D, et al.
J Clin Invest
. 2024 Nov;
135(3).
PMID: 39589795
The function of the spike protein N terminal domain (NTD) in coronavirus (CoV) infections is poorly understood. However, some rare antibodies that target the SARS-CoV-2 NTD potently neutralize the virus....
3.
Akther F, Martinez D
Sci Immunol
. 2024 Sep;
9(99):eads7640.
PMID: 39241056
Multi-omic analysis deciphers the impact of cell-intrinsic and systemic metabolomes on dengue vaccination immunogenicity.
4.
Pena-Hernandez M, Alfajaro M, Filler R, Moriyama M, Keeler E, Ranglin Z, et al.
Nat Microbiol
. 2024 Jul;
9(8):2038-2050.
PMID: 39075235
Circulating bat coronaviruses represent a pandemic threat. However, our understanding of bat coronavirus pathogenesis and transmission potential is limited by the lack of phenotypically characterized strains. We created molecular clones...
5.
Martinez D, Moreira F, Catanzaro N, Diefenbacher M, Zweigart M, Gully K, et al.
Sci Transl Med
. 2024 May;
16(748):eadj4504.
PMID: 38776389
Despite the wide availability of several safe and effective vaccines that prevent severe COVID-19, the persistent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) that...
6.
Dillard J, Taft-Benz S, Knight A, Anderson E, Pressey K, Parotti B, et al.
Nat Commun
. 2024 May;
15(1):3738.
PMID: 38702297
Whole virus-based inactivated SARS-CoV-2 vaccines adjuvanted with aluminum hydroxide have been critical to the COVID-19 pandemic response. Although these vaccines are protective against homologous coronavirus infection, the emergence of novel...
7.
Schafer A, Marzi A, Furuyama W, Catanzaro N, Nguyen C, Haddock E, et al.
Cell Rep
. 2024 Apr;
43(5):114127.
PMID: 38652660
Ebola virus (EBOV), a major global health concern, causes severe, often fatal EBOV disease (EVD) in humans. Host genetic variation plays a critical role, yet the identity of host susceptibility...
8.
Montoya B, Melo-Silva C, Tang L, Kafle S, Lidskiy P, Bajusz C, et al.
Mol Ther
. 2024 Apr;
32(6):1790-1804.
PMID: 38605519
The role of CD8 T cells in SARS-CoV-2 pathogenesis or mRNA-LNP vaccine-induced protection from lethal COVID-19 is unclear. Using mouse-adapted SARS-CoV-2 virus (MA30) in C57BL/6 mice, we show that CD8...
9.
Seo J, Martinez D
Sci Immunol
. 2024 Apr;
9(94):eadp4669.
PMID: 38579015
The hierarchy of immunosuppression predicts SARS-CoV-2 time to clearance and intrahost viral evolution.
10.
Malewana R, Stalls V, May A, Lu X, Martinez D, Schafer A, et al.
bioRxiv
. 2024 Jan;
PMID: 38187726
Immunization with mRNA or viral vectors encoding spike with diproline substitutions (S-2P) has provided protective immunity against severe COVID-19 disease. How immunization with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)...