David Patsouris
Overview
Explore the profile of David Patsouris including associated specialties, affiliations and a list of published articles.
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26
Citations
1803
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Recent Articles
1.
Abdullahi A, Wang V, Auger C, Patsouris D, Amini-Nik S, Jeschke M
Shock
. 2019 Jun;
53(4):476-484.
PMID: 31232864
Severely burned patients suffer from a hypermetabolic syndrome that can last for years after the injury has resolved. The underlying cause of these metabolic alterations most likely involves the persistent...
2.
Abdullahi A, Auger C, Stanojcic M, Patsouris D, Parousis A, Epelman S, et al.
Ann Surg
. 2017 Aug;
269(3):554-563.
PMID: 28817438
Objective: The aim of this study was to uncover the mediators and mechanistic events that facilitate the browning of white adipose tissue (WAT) in response to burns. Background: In hypermetabolic...
3.
Qi P, Abdullahi A, Stanojcic M, Patsouris D, Jeschke M
Sci Rep
. 2016 Dec;
6:38707.
PMID: 27982130
Recent discoveries have highlighted the novel metabolic functions of adipose tissue in enhancing hypermetabolism after trauma. As the exact function and expression profiles of serum lipids and free fatty acids...
4.
Abdullahi A, Stanojcic M, Parousis A, Patsouris D, Jeschke M
Shock
. 2016 Oct;
47(4):506-513.
PMID: 27755507
The endoplasmic reticulum (ER) is a critical organelle that synthesizes secretory proteins and serves as the main calcium storage site of the cell. The accumulation of unfolded proteins at the...
5.
Chirico E, Di Cataldo V, Chauveau F, Geloen A, Patsouris D, Theze B, et al.
J Physiol
. 2016 Sep;
594(23):6969-6985.
PMID: 27641234
Key Points: Vascular brain lesions and atherosclerosis are two similar conditions that are characterized by increased inflammation and oxidative stress. Non-invasive imaging in a murine model of atherosclerosis showed vascular...
6.
Diao L, Patsouris D, Sadri A, Dai X, Amini-Nik S, Jeschke M
Mol Med
. 2016 Jan;
21(1):959-968.
PMID: 26736177
Extensively burned patients often suffer from sepsis, a complication that enhances postburn hypermetabolism and contributes to increased incidence of multiple organ failure, morbidity and mortality. Despite the clinical importance of...
7.
Jeschke M, Patsouris D, Stanojcic M, Abdullahi A, Rehou S, Pinto R, et al.
EBioMedicine
. 2015 Dec;
2(10):1536-48.
PMID: 26629550
Over the last decades advancements have improved survival and outcomes of severely burned patients except one population, elderly. The Lethal Dose 50 (LD50) burn size in elderly has remained the...
8.
Patsouris D, Qi P, Abdullahi A, Stanojcic M, Chen P, Parousis A, et al.
Cell Rep
. 2015 Nov;
13(8):1538-44.
PMID: 26586436
Burn is accompanied by long-lasting immuno-metabolic alterations referred to as hypermetabolism that are characterized by a considerable increase in resting energy expenditure and substantial whole-body catabolism. In burned patients, the...
9.
Millon A, Sigovan M, Boussel L, Mathevet J, Louzier V, Paquet C, et al.
PLoS One
. 2015 Nov;
10(11):e0141880.
PMID: 26575029
Objective: Atherosclerotic plaque development in the arterial wall is the result of complex interaction between the wall's endothelial layer and blood hemodynamics. However, the interaction between hemodynamic parameters and inflammation...
10.
Bogdanovic E, Kraus N, Patsouris D, Diao L, Wang V, Abdullahi A, et al.
J Cell Mol Med
. 2014 Nov;
19(1):82-91.
PMID: 25381905
The endoplasmic reticulum (ER) is an organelle important for protein synthesis and folding, lipid synthesis and Ca(2+) homoeostasis. Consequently, ER stress or dysfunction affects numerous cellular processes and has been...