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David M Waag

Explore the profile of David M Waag including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 396
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Recent Articles
1.
Amemiya K, Dankmeyer J, Bernhards R, Fetterer D, Waag D, Worsham P, et al.
Front Cell Infect Microbiol . 2021 Dec; 11:745325. PMID: 34888257
Successful bacterial pathogens have evolved to avoid activating an innate immune system in the host that responds to the pathogen through distinct Toll-like receptors (TLRs). The general class of biochemical...
2.
Chiang C, Zhong Y, Ward M, Lane D, Kenny T, Rosario-Acevedo R, et al.
Front Microbiol . 2021 May; 12:625211. PMID: 33967974
, the causative agent of glanders, is a gram-negative intracellular bacterium. Depending on different routes of infection, the disease is manifested by pneumonia, septicemia, and chronic infections of the skin....
3.
Waag D, Chance T, Trevino S, Rossi F, Fetterer D, Amemiya K, et al.
Microb Pathog . 2021 Apr; 155:104919. PMID: 33915206
Burkholderia mallei is a gram-negative obligate animal pathogen that causes glanders, a highly contagious and potentially fatal disease of solipeds including horses, mules, and donkeys. Humans are also susceptible, and...
4.
Trevino S, Dankmeyer J, Fetterer D, Klimko C, Raymond J, Moreau A, et al.
PLoS Negl Trop Dis . 2021 Feb; 15(2):e0009125. PMID: 33571211
Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a major cause of sepsis and mortality in endemic regions of Southeast Asia and Northern Australia. B. pseudomallei is a potential...
5.
Amemiya K, Zeng X, Bearss J, Cote C, Soffler C, Bernhards R, et al.
Trop Med Infect Dis . 2020 May; 5(2). PMID: 32365605
and are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently, there are no vaccines for these two diseases. Animal models have been developed to evaluate vaccines and...
6.
Amemiya K, Dankmeyer J, Bearss J, Zeng X, Stonier S, Soffler C, et al.
BMC Immunol . 2020 Feb; 21(1):5. PMID: 32013893
Background: Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia pseudomallei. Diagnosis of melioidosis is often difficult because of the...
7.
Trevino S, Klimko C, Reed M, Aponte-Cuadrado M, Hunter M, Shoe J, et al.
PLoS One . 2018 Dec; 13(11):e0208277. PMID: 30500862
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate...
8.
Moustafa D, Scarff J, Garcia P, Cassidy S, DiGiandomenico A, Waag D, et al.
PLoS One . 2015 Jul; 10(7):e0132032. PMID: 26148026
Burkholderia pseudomallei and Burkholderia mallei are the etiologic agents of melioidosis and glanders, respectively. These bacteria are highly infectious via the respiratory route and can cause severe and often fatal...
9.
Welkos S, Klimko C, Kern S, Bearss J, Bozue J, Bernhards R, et al.
PLoS One . 2015 Apr; 10(4):e0124667. PMID: 25909629
Burkholderia pseudomallei, the etiologic agent of melioidosis, is a gram-negative facultative intracellular bacterium. This bacterium is endemic in Southeast Asia and Northern Australia and can infect humans and animals by...
10.
Waag D
Antimicrob Agents Chemother . 2015 Feb; 59(4):2236-41. PMID: 25645854
Burkholderia mallei, the causative agent of glanders, is a CDC Tier 1 Select Agent for which there is no preventive vaccine and antibiotic therapy is difficult. In this study, we...