David DeShazer
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Explore the profile of David DeShazer including associated specialties, affiliations and a list of published articles.
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69
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2655
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Recent Articles
1.
Mou S, Savchenko V, Filz V, Bottcher T, DeShazer D
Front Microbiol
. 2024 Oct;
15:1474033.
PMID: 39469462
Melioidosis is caused by , an opportunistic Gram-negative pathogen that inhabits soil and water in tropical and subtropical regions. infections often occur following contact with contaminated water or soil or...
2.
Cote C, Mlynek K, Klimko C, Biryukov S, Mou S, Hunter M, et al.
Emerg Infect Dis
. 2024 Sep;
30(10):2056-2069.
PMID: 39320153
In the United States in 2021, an outbreak of 4 cases of Burkholderia pseudomallei, the etiologic agent of melioidosis and a Tier One Select Agent (potential for deliberate misuse and...
3.
Klimko C, Welkos S, Shoe J, Mou S, Hunter M, Rill N, et al.
Antibiotics (Basel)
. 2022 Dec;
11(12).
PMID: 36551342
The microbial pathogens and are unrelated bacteria, yet both are the etiologic agents of naturally occurring diseases in animals and humans and are classified as Tier 1 potential biothreat agents....
4.
Klimko C, Shoe J, Rill N, Hunter M, Dankmeyer J, Talyansky Y, et al.
Front Microbiol
. 2022 Sep;
13:965572.
PMID: 36060756
, the gram-negative bacterium that causes melioidosis, is notoriously difficult to treat with antibiotics. A significant effort has focused on identifying protective vaccine strategies to prevent melioidosis. However, when used...
5.
Biryukov S, Cote C, Klimko C, Dankmeyer J, Rill N, Shoe J, et al.
Front Microbiol
. 2022 Sep;
13:965518.
PMID: 36060742
and the closely related species, , produce similar multifaceted diseases which range from rapidly fatal to protracted and chronic, and are a major cause of mortality in endemic regions. Besides...
6.
Chua J, Nguyenkhoa E, Mou S, Tobery S, Friedlander A, DeShazer D
Infect Immun
. 2022 Jul;
90(8):e0015922.
PMID: 35862734
Burkholderia pseudomallei, the causative agent of melioidosis, is classified by the CDC as a tier 1 select agent, and work involving it must be performed in a biosafety level 3...
7.
Okaro U, Mou S, Lenkoue G, Williams J, Bonagofski A, Larson P, et al.
Microbiology (Reading)
. 2022 Mar;
168(3).
PMID: 35293855
Type IV pili are involved in adhesion, twitching motility, aggregation, biofilm formation and virulence in a variety of Gram-negative bacteria. the causative agent of melioidosis and a Tier 1 biological...
8.
Amemiya K, Dankmeyer J, Bernhards R, Fetterer D, Waag D, Worsham P, et al.
Front Cell Infect Microbiol
. 2021 Dec;
11:745325.
PMID: 34888257
Successful bacterial pathogens have evolved to avoid activating an innate immune system in the host that responds to the pathogen through distinct Toll-like receptors (TLRs). The general class of biochemical...
9.
Mou S, Jenkins C, Okaro U, Dhummakupt E, Mach P, DeShazer D
Microbiol Spectr
. 2021 Jun;
9(1):e0010221.
PMID: 34160272
Burkholderia pseudomallei is an opportunistic pathogen that is responsible for the disease melioidosis in humans and animals. The microbe is a tier 1 select agent because it is highly infectious...
10.
Welkos S, Blanco I, Okaro U, Chua J, DeShazer D
Virulence
. 2020 Aug;
11(1):1041-1058.
PMID: 32835600
Burkholderia pseudomallei: is the etiological agent of the disease melioidosis and is a Tier 1 select agent. It survives and replicates inside phagocytic cells by escaping from the endocytic vacuole,...