Carl Soffler
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Explore the profile of Carl Soffler including associated specialties, affiliations and a list of published articles.
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14
Citations
109
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Recent Articles
1.
Hilliard J, Jakielaszek C, Mannino F, Hossain M, Qian L, Fishman C, et al.
Antimicrob Agents Chemother
. 2024 Feb;
68(3):e0149723.
PMID: 38358266
is a Gram-positive Centers for Disease Control and Prevention category "A" biothreat pathogen. Without early treatment, inhalation of anthrax spores with progression to inhalational anthrax disease is associated with high...
2.
Trevino S, Dankmeyer J, Fetterer D, Klimko C, Raymond J, Moreau A, et al.
PLoS Negl Trop Dis
. 2021 Feb;
15(2):e0009125.
PMID: 33571211
Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a major cause of sepsis and mortality in endemic regions of Southeast Asia and Northern Australia. B. pseudomallei is a potential...
3.
Amemiya K, Zeng X, Bearss J, Cote C, Soffler C, Bernhards R, et al.
Trop Med Infect Dis
. 2020 May;
5(2).
PMID: 32365605
and are Gram-negative, facultative intracellular bacteria that cause melioidosis and glanders, respectively. Currently, there are no vaccines for these two diseases. Animal models have been developed to evaluate vaccines and...
4.
Klimko C, Trevino S, Moreau A, Cuadrado M, Meyer J, Fetterer D, et al.
Pathogens
. 2020 Feb;
9(2).
PMID: 32054106
Mouse models have been used to generate critical data for many infectious diseases. In the case of , mouse models have been invaluable for bacterial pathogenesis studies as well as...
5.
Amemiya K, Dankmeyer J, Bearss J, Zeng X, Stonier S, Soffler C, et al.
BMC Immunol
. 2020 Feb;
21(1):5.
PMID: 32013893
Background: Melioidosis is endemic in Southeast Asia and Northern Australia and is caused by the Gram-negative, facultative intracellular pathogen Burkholderia pseudomallei. Diagnosis of melioidosis is often difficult because of the...
6.
Yi J, Simpanya M, Settles E, Shannon A, Hernandez K, Pristo L, et al.
PLoS Negl Trop Dis
. 2019 Feb;
13(2):e0006851.
PMID: 30811382
Burkholderia pseudomallei causes melioidosis, a common source of pneumonia and sepsis in Southeast Asia and Northern Australia that results in high mortality rates. A caprine melioidosis model of aerosol infection...
7.
Trevino S, Klimko C, Reed M, Aponte-Cuadrado M, Hunter M, Shoe J, et al.
PLoS One
. 2018 Dec;
13(11):e0208277.
PMID: 30500862
Mouse models have been essential to generate supporting data for the research of infectious diseases. Burkholderia pseudomallei, the etiological agent of melioidosis, has been studied using mouse models to investigate...
8.
Marley L, Soffler C, Hackett E
J Am Vet Med Assoc
. 2018 Sep;
253(6):781-787.
PMID: 30179083
OBJECTIVE To describe clinical features, diagnostic methods, treatments, and outcomes associated with ingested wire foreign bodies in the abdomen of horses. DESIGN Retrospective case series. ANIMALS 16 client-owned horses with...
9.
Soffler C, Bosco-Lauth A, Aboellail T, Marolf A, Bowen R
Int J Exp Pathol
. 2014 Feb;
95(2):101-19.
PMID: 24571408
Melioidosis is a severe suppurative to granulomatous infection caused by Burkholderia pseudomallei. The disease is endemic to South-East Asia and Northern Australasia and is also of interest as a potential...
10.
Gonzalez-Juarrero M, Bosco-Lauth A, Podell B, Soffler C, Brooks E, Izzo A, et al.
Tuberculosis (Edinb)
. 2013 Jul;
93(5):558-64.
PMID: 23850102
The use of animal models is essential in testing the efficacy for novel therapies against tuberculosis (TB). Calves and non-human primates are examples of large animal models currently used to...