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David M Selva

Explore the profile of David M Selva including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 867
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Recent Articles
11.
Saez-Lopez C, Barbosa-Desongles A, Hernandez C, Dyer R, Innis S, Simo R, et al.
Endocrinology . 2017 Mar; 158(3):545-559. PMID: 28359088
Low plasma sex hormone-binding globulin (SHBG) levels are a hallmark in chronic metabolic diseases, including nonalcoholic fatty liver disease (NAFLD), which represents a spectrum of disease ranging from hepatocellular steatosis...
12.
Saez-Lopez C, Rivera-Gimenez M, Hernandez C, Simo R, Selva D
Endocrinology . 2015 Oct; 156(12):4571-81. PMID: 26441241
Low plasma sex hormone-binding globulin (SHBG) levels in overweight individuals are a biomarker for the metabolic syndrome and are predictive of type 2 diabetes and cardiovascular disease risk. There are...
13.
Simo R, Saez-Lopez C, Barbosa-Desongles A, Hernandez C, Selva D
Trends Endocrinol Metab . 2015 Jun; 26(7):376-83. PMID: 26044465
Sex hormone-binding globulin (SHBG) is produced and secreted by the liver into the bloodstream where it binds sex steroids and regulates their bioavailability. Traditionally, body mass index (BMI) was thought...
14.
Simo R, Saez-Lopez C, Lecube A, Hernandez C, Fort J, Selva D
Endocrinology . 2014 May; 155(8):2820-30. PMID: 24828613
Epidemiological studies have shown that plasma SHBG levels correlate with plasma adiponectin levels, both in men and women. There are no reports describing any molecular mechanism by which adiponectin regulates...
15.
Simo R, Hernandez C, Saez-Lopez C, Soldevila B, Puig-Domingo M, Selva D
PLoS One . 2014 Jan; 9(1):e85753. PMID: 24465683
Overproduction of zinc-α2-glycoprotein by adipose tissue is crucial in accounting for the lipolysis occurring in cancer cachexia of certain malignant tumors. The main aim of this study was to explore...
16.
Saez-Lopez C, Soriguer F, Hernandez C, Rojo-Martinez G, Rubio-Martin E, Simo R, et al.
Mol Nutr Food Res . 2013 Oct; 58(4):760-7. PMID: 24142580
Scope: Low circulating sex hormone-binding globulin (SHBG) is an independent risk factor for cardiovascular disease. Mediterranean diet has been associated with a decreased risk of cardiovascular disease. We aimed to...
17.
Barbosa-Desongles A, Hernandez C, de Torres I, Munell F, Poupon M, Simo R, et al.
PLoS One . 2013 Sep; 8(9):e74179. PMID: 24058525
Type 2 diabetes has been associated with decreased risk of prostate cancer in observational studies, and this inverse association has been recently confirmed in several large cohort studies. However the...
18.
Barbosa-Desongles A, Hernandez C, Simo R, Selva D
Am J Physiol Cell Physiol . 2013 May; 305(3):C355-9. PMID: 23720021
Evidence from the literature suggests that testosterone plays an important role in visceral fat accumulation since both men and women with hyperandrogenism accumulate more adipose tissue in the abdominal cavity...
19.
Simo R, Barbosa-Desongles A, Hernandez C, Selva D
Mol Endocrinol . 2012 Aug; 26(11):1917-27. PMID: 22902540
Patients suffering from low-grade chronic inflammatory diseases, such as rheumatoid arthritis, osteoarthritis, diabetes, and obesity, have low plasma sex hormone-binding globulin (SHBG) levels. These diseases are characterized among other features...
20.
Simo R, Barbosa-Desongles A, Saez-Lopez C, Lecube A, Hernandez C, Selva D
Mol Endocrinol . 2012 Feb; 26(3):438-46. PMID: 22301786
The reason why obesity (a chronic low-grade inflammatory disease) is associated with low levels of sex hormone-binding globulin (SHBG) remains to be elucidated. The present study provides evidence that TNFα...