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David M P De Oliveira

Explore the profile of David M P De Oliveira including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1244
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Recent Articles
1.
McEwan T, De Oliveira D, Stares E, Hartley-Tassell L, Day C, Proctor E, et al.
FASEB J . 2024 Oct; 38(20):e70123. PMID: 39436142
Tissue injury, including extracellular matrix (ECM) degradation, is a hallmark of group A Streptococcus (GAS) skin infection and is partially mediated by M proteins which possess lectin-like properties. Hyaluronic acid...
2.
Proctor E, Frost H, Satapathy S, Botquin G, Urbaniec J, Gorman J, et al.
J Biol Chem . 2024 Jan; 300(2):105623. PMID: 38176650
Group A Streptococcal M-related proteins (Mrps) are dimeric α-helical-coiled-coil cell membrane-bound surface proteins. During infection, Mrp recruit the fragment crystallizable region of human immunoglobulin G via their A-repeat regions to...
3.
Brouwer S, Rivera-Hernandez T, Curren B, Harbison-Price N, De Oliveira D, Jespersen M, et al.
Nat Rev Microbiol . 2023 Jul; 21(9):619. PMID: 37400634
No abstract available.
4.
Mu A, Klare W, Baines S, Ignatius Pang C, Guerillot R, Harbison-Price N, et al.
Nat Commun . 2023 Mar; 14(1):1530. PMID: 36934086
Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, with antibiotic resistance dramatically increasing this mortality risk. To develop...
5.
Brouwer S, Rivera-Hernandez T, Curren B, Harbison-Price N, De Oliveira D, Jespersen M, et al.
Nat Rev Microbiol . 2023 Mar; 21(7):431-447. PMID: 36894668
Streptococcus pyogenes (Group A Streptococcus; GAS) is exquisitely adapted to the human host, resulting in asymptomatic infection, pharyngitis, pyoderma, scarlet fever or invasive diseases, with potential for triggering post-infection immune...
6.
Davies M, Keller N, Brouwer S, Jespersen M, Cork A, Hayes A, et al.
Nat Commun . 2023 Feb; 14(1):1051. PMID: 36828918
A new variant of Streptococcus pyogenes serotype M1 (designated 'M1') has been reported in the United Kingdom, linked with seasonal scarlet fever surges, marked increase in invasive infections, and exhibiting...
7.
Li G, Walker M, De Oliveira D
Microorganisms . 2023 Jan; 11(1). PMID: 36677316
, and are both common commensals and major opportunistic human pathogens. In recent decades, these bacteria have acquired broad resistance to several major classes of antibiotics, including commonly employed glycopeptides....
8.
Brouwer S, Jespersen M, Ong C, De Oliveira D, Keller B, Cork A, et al.
mBio . 2022 Apr; 13(3):e0067622. PMID: 35467425
The nasopharynx and the skin are the major oxygen-rich anatomical sites for colonization by the human pathogen Streptococcus pyogenes (group A Streptococcus [GAS]). To establish infection, GAS must survive oxidative...
9.
De Oliveira D, Keller B, Hayes A, Ong C, Harbison-Price N, El-Deeb I, et al.
Antibiotics (Basel) . 2022 Apr; 11(4). PMID: 35453201
Gram-positive bacteria do not produce lipopolysaccharide as a cell wall component. As such, the polymyxin class of antibiotics, which exert bactericidal activity against Gram-negative pathogens, are ineffective against Gram-positive bacteria....
10.
De Oliveira D, Walker M
Microb Cell . 2022 Mar; 9(3):69-71. PMID: 35291313
Within intensive care units, multi-drug resistant outbreaks are a frequent cause of ventilator-associated pneumonia. During the on-going COVID-19 pandemic, patients who receive ventilator support experience a 2-fold increased risk of...