Amanda J Cork
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Explore the profile of Amanda J Cork including associated specialties, affiliations and a list of published articles.
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27
Citations
652
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Recent Articles
1.
Richter J, Cork A, Ong Y, Keller N, Hayes A, Schembri M, et al.
mBio
. 2024 Dec;
16(2):e0336624.
PMID: 39688411
Group A (GAS) is a human-adapted pathogen responsible for a variety of diseases. The GAS M1 lineage has contributed significantly to the recently reported increases in scarlet fever and invasive...
2.
Rivera-Hernandez T, Carnathan D, Richter J, Marchant P, Cork A, Elangovan G, et al.
Vaccines (Basel)
. 2024 Apr;
12(4).
PMID: 38675764
Vaccine development against group A (GAS) has gained traction in the last decade, fuelled by recognition of the significant worldwide burden of the disease. Several vaccine candidates are currently being...
3.
Mu A, Klare W, Baines S, Ignatius Pang C, Guerillot R, Harbison-Price N, et al.
Nat Commun
. 2023 Mar;
14(1):1530.
PMID: 36934086
Even in the setting of optimal resuscitation in high-income countries severe sepsis and septic shock have a mortality of 20-40%, with antibiotic resistance dramatically increasing this mortality risk. To develop...
4.
Davies M, Keller N, Brouwer S, Jespersen M, Cork A, Hayes A, et al.
Nat Commun
. 2023 Feb;
14(1):1051.
PMID: 36828918
A new variant of Streptococcus pyogenes serotype M1 (designated 'M1') has been reported in the United Kingdom, linked with seasonal scarlet fever surges, marked increase in invasive infections, and exhibiting...
5.
Brouwer S, Jespersen M, Ong C, De Oliveira D, Keller B, Cork A, et al.
mBio
. 2022 Apr;
13(3):e0067622.
PMID: 35467425
The nasopharynx and the skin are the major oxygen-rich anatomical sites for colonization by the human pathogen Streptococcus pyogenes (group A Streptococcus [GAS]). To establish infection, GAS must survive oxidative...
6.
De Oliveira D, Keller B, Hayes A, Ong C, Harbison-Price N, El-Deeb I, et al.
Antibiotics (Basel)
. 2022 Apr;
11(4).
PMID: 35453201
Gram-positive bacteria do not produce lipopolysaccharide as a cell wall component. As such, the polymyxin class of antibiotics, which exert bactericidal activity against Gram-negative pathogens, are ineffective against Gram-positive bacteria....
7.
De Oliveira D, Forde B, Phan M, Steiner B, Zhang B, Zuegg J, et al.
mBio
. 2022 Jan;
13(1):e0351721.
PMID: 35012353
Acinetobacter baumannii causes high mortality in ventilator-associated pneumonia patients, and antibiotic treatment is compromised by multidrug-resistant strains resistant to β-lactams, carbapenems, cephalosporins, polymyxins, and tetracyclines. Among COVID-19 patients receiving ventilator...
8.
Richter J, Monteleone M, Cork A, Barnett T, Nizet V, Brouwer S, et al.
Immunol Cell Biol
. 2021 Aug;
99(10):1040-1052.
PMID: 34462965
Group A Streptococcus (GAS) is a Gram-positive bacterial pathogen that causes an array of infectious diseases in humans. Accumulating clinical evidence suggests that proinflammatory interleukin (IL)-1β signaling plays an important...
9.
Loh J, Rivera-Hernandez T, McGregor R, Khemlani A, Tay M, Cork A, et al.
Sci Rep
. 2021 Feb;
11(1):4353.
PMID: 33623073
Pili of Group A Streptococcus (GAS) are surface-exposed structures involved in adhesion and colonisation of the host during infection. The major protein component of the GAS pilus is the T-antigen,...
10.
Rivera-Hernandez T, Carnathan D, Jones S, Cork A, Davies M, Moyle P, et al.
mBio
. 2020 Dec;
11(6).
PMID: 33262263
No abstract available.