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David L Paterson

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Articles 519
Citations 23482
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Recent Articles
1.
Soriano A, Paterson D, Thalhalmmer F, Kluge S, Viale P, Akrich B, et al.
Diagn Microbiol Infect Dis . 2025 Feb; 111(4):116737. PMID: 39955850
Background: Ceftolozane/tazobactam (C/T) real-world use was examined in a global population of critical care patients treated in intensive care unit settings. Methods: The Study of Prescribing patterns and Effectiveness of...
2.
Mahar R, McGlothlin A, Dymock M, Barina L, Bonten M, Bowen A, et al.
Trials . 2025 Feb; 26(1):49. PMID: 39934879
Platform trials have become widely adopted across multiple disease areas over recent years, however, guidelines for operationalising these trials have not kept pace. We outline a series of documents that...
3.
Soriano A, Paterson D, Thalhammer F, Kluge S, Viale P, Watanabe A, et al.
J Glob Antimicrob Resist . 2025 Jan; 41:272-279. PMID: 39864656
Objectives: Antibacterial-resistant gram-negative hospital-acquired infections result in significant morbidity and mortality. In clinical trials, ceftolozane/tazobactam (C/T) has been effective against these infections; however, real-world findings are limited. Methods: SPECTRA was...
4.
Aslan A, Kara E, Koksal G, Bilir Y, Saracoglu K, Eser F, et al.
Int J Antimicrob Agents . 2025 Jan; 65(3):107446. PMID: 39826571
Objective: Both vancomycin (VAN) and teicoplanin (TEI) augment the risk of acute kidney injury (AKI) when combined with piperacillin-tazobactam (TZP). We aimed to compare the risk of AKI among patients...
5.
Stewart A, Harris P, Edwards F, Kiani B, Paterson D, Laupland K
Infection . 2025 Jan; PMID: 39747735
Purpose: Klebsiella pneumoniae is a common cause of hospital- and community-acquired infection and can readily acquire multiple antimicrobial resistance determinants leading to poor health outcomes. We define the contemporary burden...
6.
Stewart A, Edwards F, Harris P, Paterson D, Laupland K
Eur J Clin Microbiol Infect Dis . 2024 Dec; 44(2):427-436. PMID: 39692935
Background: Fusobacterium species are anaerobic Gram-negative bacilli which are uncommon causes of bloodstream infection (BSI). This genus commonly colonises the gastrointestinal tract and can result in significant morbidity. Methods: All...
7.
Khatri D, Falconer N, Coulter S, Gray L, Paterson D, Freeman C
Am J Infect Control . 2024 Dec; PMID: 39672272
Background: Antibiograms can optimize empirical antibiotic prescribing; however, they are not readily available for residential aged care facilities (RACFs) in Queensland, Australia. This study aimed to determine whether alternatively available...
8.
Shou Y, Yeo J, Pang A, Paterson D, Mo Y
BMJ Open . 2024 Nov; 14(11):e082096. PMID: 39581733
Objectives: Randomised trials for the management of drug-resistant infections are challenging to conduct as target patient populations often lack decision-making capacity, and enrolment windows are typically short. Improving informed consent...
9.
Gibbs A, Laupland K, Edwards F, Ling W, Channon-Wells S, Harley D, et al.
Pediatrics . 2024 Sep; 154(4). PMID: 39327952
Objectives: Enterobacterales bloodstream infections (E-BSI) cause a significant burden of disease in children and are associated with antimicrobial resistance. We assessed temporal changes in the population-based incidence of E-BSI in...
10.
Khatri D, Falconer N, Coulter S, Gray L, Paterson D, Freeman C
Infect Control Hosp Epidemiol . 2024 Sep; :1-7. PMID: 39323353
Objective: Knowledge of local antibiotic resistance data, provided by antibiograms (a cumulative summary of in vitro-antimicrobial-susceptibility-test results), can aid prescribing of appropriate empirical antibiotics. This study aimed to explore the...