David M Brass
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Explore the profile of David M Brass including associated specialties, affiliations and a list of published articles.
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1248
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Recent Articles
11.
Hollingsworth J, Maruoka S, Boon K, Garantziotis S, Li Z, Tomfohr J, et al.
J Clin Invest
. 2016 May;
126(5):2012.
PMID: 27135881
No abstract available.
12.
Lai P, Hofmann O, Baron R, Cernadas M, Meng Q, Bresler H, et al.
PLoS One
. 2013 May;
8(5):e62910.
PMID: 23675439
Rationale: Endotoxin is a near ubiquitous environmental exposure that that has been associated with both asthma and chronic obstructive pulmonary disease (COPD). These obstructive lung diseases have a complex pathophysiology,...
13.
Brass D, Spencer J, Li Z, Potts-Kant E, Reilly S, Dunkel M, et al.
PLoS One
. 2012 Jul;
7(7):e40789.
PMID: 22815821
Acute exacerbations of pulmonary fibrosis are characterized by rapid decrements in lung function. Environmental factors that may contribute to acute exacerbations remain poorly understood. We have previously demonstrated that exposure...
14.
Lindsey J, Ganguly K, Brass D, Li Z, Potts E, Degan S, et al.
Am J Respir Crit Care Med
. 2011 Apr;
183(12):1644-52.
PMID: 21471107
Rationale: Previously, we demonstrated a candidate region for susceptibility to airspace enlargement on mouse chromosome 5. However, the specific candidate genes within this region accounting for emphysema-like changes remain unrecognized....
15.
Kelada S, Wilson M, Tavarez U, Kubalanza K, Borate B, Whitehead G, et al.
Am J Respir Cell Mol Biol
. 2011 Mar;
45(4):817-24.
PMID: 21378263
Asthma is etiologically and clinically heterogeneous, making the genomic basis of asthma difficult to identify. We exploited the strain-dependence of a murine model of allergic airway disease to identify different...
16.
Brass D, McGee S, Dunkel M, Reilly S, Tobolewski J, Sabo-Attwood T, et al.
Am J Physiol Lung Cell Mol Physiol
. 2010 Aug;
299(5):L664-71.
PMID: 20729388
Accumulating evidence suggests that gender can have a profound effect on incidence and severity of a variety of pulmonary diseases. To address the influence of gender on the development of...
17.
Rawlins E, Okubo T, Xue Y, Brass D, Auten R, Hasegawa H, et al.
Cell Stem Cell
. 2009 Jun;
4(6):525-34.
PMID: 19497281
To directly test the contribution of Scgb1a1(+) Clara cells to postnatal growth, homeostasis, and repair of lung epithelium, we generated a Scgb1a1-CreER "knockin" mouse for lineage-tracing these cells. Under all...
18.
Brass D, Wise A, Schwartz D
Semin Respir Crit Care Med
. 2009 Feb;
29(6):603-9.
PMID: 19221958
Diffuse lung disease (DLD), also known as interstitial lung disease (ILD), comprises a group of relatively rare but devastating lung diseases that involve varying degrees of acute and chronic inflammation,...
19.
Boon K, Tomfohr J, Bailey N, Garantziotis S, Li Z, Brass D, et al.
BMC Genomics
. 2008 Dec;
9:598.
PMID: 19077247
Background: The study of genome-wide DNA methylation changes has become more accessible with the development of various array-based technologies though when studying species other than human the choice of applications...
20.
Hollingsworth J, Maruoka S, Boon K, Garantziotis S, Li Z, Tomfohr J, et al.
J Clin Invest
. 2008 Sep;
118(10):3462-9.
PMID: 18802477
Asthma is a complex heritable disease that is increasing in prevalence and severity, particularly in developed countries such as the United States, where 11% of the population is affected. The...