David M Brass
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Explore the profile of David M Brass including associated specialties, affiliations and a list of published articles.
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36
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1248
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Recent Articles
1.
Binkowski B, Klamer Z, Gao C, Staal B, Repesh A, Tran H, et al.
Sci Adv
. 2025 Mar;
11(10):eadt0029.
PMID: 40053601
Pancreatic ductal adenocarcinoma (PDAC) tumor heterogeneity impedes the development of biomarker assays for early disease detection. We hypothesized that PDAC cell subpopulations could be identified by aberrant glycan signatures in...
2.
Binkowski B, Klamer Z, Gao C, Staal B, Repesh A, Tran H, et al.
bioRxiv
. 2024 Sep;
PMID: 39229066
Pancreatic ductal adenocarcinoma (PDAC) tumor heterogeneity impedes the development of biomarker assays suitable for early disease detection that would improve patient outcomes. The CA19-9 glycan is currently used as a...
3.
Todd J, Weber J, Kelly F, Neely M, Nagler A, Carmack D, et al.
J Heart Lung Transplant
. 2023 Mar;
42(6):741-749.
PMID: 36941179
Background: Chronic lung allograft dysfunction (CLAD) increases morbidity and mortality for lung transplant recipients. Club cell secretory protein (CCSP), produced by airway club cells, is reduced in the bronchoalveolar lavage...
4.
Langel S, Kelly F, Brass D, Nagler A, Carmack D, Tu J, et al.
Cell Death Discov
. 2022 Feb;
8(1):64.
PMID: 35169120
Diacetyl (DA) is an α-diketone that is used to flavor microwave popcorn, coffee, and e-cigarettes. Occupational exposure to high levels of DA causes impaired lung function and obstructive airway disease....
5.
Dubini M, Marraccini P, Brass D, Patrini L, Riboldi L
Med Lav
. 2020 Jul;
111(3):203-209.
PMID: 32624562
Background: There are several potential sensitizers in the bakery environment and wheat flour appears to be the dominant sensitizer in most bakeries. Apart from traditional drug therapy or a change...
6.
Kelly F, Weinberg K, Nagler A, Nixon A, Star M, Todd J, et al.
Toxicol Sci
. 2019 Mar;
169(2):534-542.
PMID: 30851105
2,3-Butanedione (DA), a component of artificial butter flavoring, is associated with the development of occupational bronchiolitis obliterans (BO), a disease of progressive airway fibrosis resulting in lung function decline. Neutrophilic...
7.
Brass D, Gwinn W, Valente A, Kelly F, Brinkley C, Nagler A, et al.
Am J Respir Cell Mol Biol
. 2017 Mar;
56(6):784-795.
PMID: 28248570
Bronchiolitis obliterans (BO) is an increasingly important lung disease characterized by fibroproliferative airway lesions and decrements in lung function. Occupational exposure to the artificial food flavoring ingredient diacetyl, commonly used...
8.
Brass D, Palmer S
Toxicology
. 2017 Feb;
388:15-20.
PMID: 28232124
Diacetyl (DA; 2,3-butanedione), with the chemical formula (CHCO) is a volatile organic compound with a deep yellow color and a strong buttery flavor and aroma. These properties have made DA...
9.
Foster M, Gwinn W, Kelly F, Brass D, Valente A, Moseley M, et al.
J Proteome Res
. 2016 Dec;
16(2):538-549.
PMID: 27966365
Occupational exposures to the diketone flavoring agent, diacetyl, have been associated with bronchiolitis obliterans, a rare condition of airway fibrosis. Model studies in rodents have suggested that the airway epithelium...
10.
Brass D, Spencer J, Li Z, Potts-Kant E, Reilly S, Dunkel M, et al.
PLoS One
. 2016 May;
11(5):e0155388.
PMID: 27158821
No abstract available.