David Jimenez-Morales
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Explore the profile of David Jimenez-Morales including associated specialties, affiliations and a list of published articles.
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36
Citations
631
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Recent Articles
1.
An Z, Fan Q, Wang L, Yoda H, Barata M, Jimenez-Morales D, et al.
Neuro Oncol
. 2024 Sep;
27(2):383-397.
PMID: 39248287
Background: Co-amplification of the epidermal growth factor receptor (EGFR) and EGFRvIII, a tumor-specific truncation mutant of EGFR, represent hallmark genetic lesions in glioblastoma. Methods: We used phospho-proteomics, RNA-sequencing, TCGA data,...
2.
Bielow C, Hoffmann N, Jimenez-Morales D, Van Den Bossche T, Vizcaino J, Tabb D, et al.
J Am Soc Mass Spectrom
. 2024 Jun;
35(8):1875-1882.
PMID: 38918936
Mass spectrometry is a powerful technique for analyzing molecules in complex biological samples. However, inter- and intralaboratory variability and bias can affect the data due to various factors, including sample...
3.
Amar D, Gay N, Jimenez-Morales D, Jean Beltran P, Ramaker M, Raja A, et al.
Cell Metab
. 2024 May;
36(6):1411-1429.e10.
PMID: 38701776
Mitochondria have diverse functions critical to whole-body metabolic homeostasis. Endurance training alters mitochondrial activity, but systematic characterization of these adaptations is lacking. Here, the Molecular Transducers of Physical Activity Consortium...
4.
Many G, Sanford J, Sagendorf T, Hou Z, Nigro P, Whytock K, et al.
Nat Metab
. 2024 May;
6(5):963-979.
PMID: 38693320
Subcutaneous white adipose tissue (scWAT) is a dynamic storage and secretory organ that regulates systemic homeostasis, yet the impact of endurance exercise training (ExT) and sex on its molecular landscape...
5.
Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang G, Krogan N, et al.
Mol Biol Cell
. 2023 Dec;
35(3):ar27.
PMID: 38117589
The intracellular bacterial pathogen () manipulates eukaryotic host ubiquitination machinery to form its replicative vacuole. While nearly 10% of 's ∼330 secreted effector proteins are ubiquitin ligases or deubiquitinases, a...
6.
Steinbach A, Bhadkamkar V, Jimenez-Morales D, Stevenson E, Jang G, Krogan N, et al.
bioRxiv
. 2023 Aug;
PMID: 37577546
The intracellular bacterial pathogen manipulates eukaryotic host ubiquitination machinery to form its replicative vacuole. While nearly 10% of 's arsenal of ~330 secreted effector proteins have been biochemically characterized as...
7.
Cakir Z, Lord S, Zhou Y, Jang G, Polacco B, Eckhardt M, et al.
Mol Cell Proteomics
. 2023 Apr;
22(5):100541.
PMID: 37019383
Apolipoprotein (apo) E4 is the major genetic risk factor for Alzheimer's disease. While neurons generally produce a minority of the apoE in the central nervous system, neuronal expression of apoE...
8.
Many G, Sanford J, Sagendorf T, Hou Z, Nigro P, Whytock K, et al.
bioRxiv
. 2023 Feb;
PMID: 36778330
Subcutaneous white adipose tissue (scWAT) is a dynamic storage and secretory organ that regulates systemic homeostasis, yet the impact of endurance exercise training and sex on its molecular landscape has...
9.
Amar D, Gay N, Jimenez-Morales D, Jean Beltran P, Ramaker M, Raja A, et al.
bioRxiv
. 2023 Jan;
PMID: 36711881
Mitochondria are adaptable organelles with diverse cellular functions critical to whole-body metabolic homeostasis. While chronic endurance exercise training is known to alter mitochondrial activity, these adaptations have not yet been...
10.
Leon K, Khalid M, Flynn R, Fontaine K, Nguyen T, Kumar G, et al.
PLoS Pathog
. 2023 Jan;
19(1):e1011070.
PMID: 36603024
Zika virus (ZIKV) infects fetal neural progenitor cells (NPCs) causing severe neurodevelopmental disorders in utero. Multiple pathways involved in normal brain development are dysfunctional in infected NPCs but how ZIKV...