David J Stillman
Overview
Explore the profile of David J Stillman including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
52
Citations
1676
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Genetic analysis argues for a coactivator function for the Saccharomyces cerevisiae Tup1 corepressor
Parnell E, Parnell T, Stillman D
Genetics
. 2021 Dec;
219(2).
PMID: 34849878
The Tup1-Cyc8 corepressor complex of Saccharomyces cerevisiae is recruited to promoters by DNA-binding proteins to repress transcription of genes, including the a-specific mating-type genes. We report here a tup1(S649F) mutant...
2.
Parnell E, Parnell T, Yan C, Bai L, Stillman D
PLoS Genet
. 2020 Dec;
16(12):e1009133.
PMID: 33382702
Transcriptional regulation of the Saccharomyces cerevisiae HO gene is highly complex, requiring a balance of multiple activating and repressing factors to ensure that only a few transcripts are produced in...
3.
Yu Y, Yarrington R, Stillman D
Nucleic Acids Res
. 2020 Oct;
48(19):10877-10889.
PMID: 33010153
The Saccharomyces cerevisiae HO gene is a model regulatory system with complex transcriptional regulation. Budding yeast divide asymmetrically and HO is expressed only in mother cells where a nucleosome eviction...
4.
Yarrington R, Yu Y, Yan C, Bai L, Stillman D
Genetics
. 2020 Apr;
215(2):407-420.
PMID: 32327563
Mediator is an essential, multisubunit complex that functions as a transcriptional coactivator in yeast and other eukaryotic organisms. Mediator has four conserved modules, Head, Middle, Tail, and Kinase, and has...
5.
Parnell E, Stillman D
Genetics
. 2019 Jun;
212(4):1181-1204.
PMID: 31167839
Activation of the promoter is highly regulated, requiring the ordered recruitment of activators and coactivators and allowing production of only a few transcripts in mother cells within a short cell...
6.
McCullough L, Pham T, Parnell T, Connell Z, Chandrasekharan M, Stillman D, et al.
Genetics
. 2019 Jan;
211(3):877-892.
PMID: 30679261
FACT (FAcilitates Chromatin Transcription/Transactions) is a histone chaperone that can destabilize or assemble nucleosomes. Acetylation of histone H3-K56 weakens a histone-DNA contact that is central to FACT activity, suggesting that...
7.
Chiaro T, Soto R, Stephens W, Kubinak J, Petersen C, Gogokhia L, et al.
Sci Transl Med
. 2017 Mar;
9(380).
PMID: 28275154
The commensal microbiota has an important impact on host health, which is only beginning to be elucidated. Despite the presence of fungal, archaeal, and viral members, most studies have focused...
8.
Yu Y, Yarrington R, Chuong E, Elde N, Stillman D
Proc Natl Acad Sci U S A
. 2016 Aug;
113(34):9575-80.
PMID: 27506791
The yeast HO endonuclease is expressed in late G1 in haploid mother cells to initiate mating-type interconversion. Cells can be arrested in G1 by nutrient deprivation or by pheromone exposure,...
9.
Nucleosomes Are Essential for Proper Regulation of a Multigated Promoter in Saccharomyces cerevisiae
Yarrington R, Goodrum J, Stillman D
Genetics
. 2015 Dec;
202(2):551-63.
PMID: 26627840
Nucleosome-depleted regions (NDRs) are present immediately adjacent to the transcription start site in most eukaryotic promoters. Here we show that NDRs in the upstream promoter region can profoundly affect gene...
10.
Yarrington R, Rudd J, Stillman D
Mol Cell Biol
. 2014 Dec;
35(4):688-98.
PMID: 25512608
Promoters often contain multiple binding sites for a single factor. The yeast HO gene contains nine highly conserved binding sites for the SCB (Swi4/6-dependent cell cycle box) binding factor (SBF)...