David J Askew
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Explore the profile of David J Askew including associated specialties, affiliations and a list of published articles.
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17
Citations
936
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Recent Articles
1.
Kinjo Y, Shibata E, Askew D, Tanaka R, Suga R, Shimono M, et al.
Environ Int
. 2024 May;
188:108725.
PMID: 38759546
Background: Lifelong health is dependent on prenatal growth and development, influenced by the placental intrauterine environment. Charged with dual functions--exchange of oxygen and nutrients as well as a barrier against...
2.
Hasunuma H, Takeuchi A, Ono R, Amimoto Y, Hwang Y, Uno I, et al.
Sci Total Environ
. 2020 Sep;
753:141585.
PMID: 32890882
There has been little study on the effect of Asian dust exposure on respiratory symptoms among children who are vulnerable to environmental factors. In this panel study, we investigated the...
3.
Myoga M, Tsuji M, Tanaka R, Shibata E, Askew D, Aiko Y, et al.
BMC Pregnancy Childbirth
. 2019 Dec;
19(1):483.
PMID: 31818260
Background: Gestational diabetes mellitus (GDM) has serious effects on both mother and child. Like Type 2 Diabetes Mellitus, it is increasing in prevalence world-wide. In addition to obesity, sleep duration...
4.
Tsuji M, Shibata E, Askew D, Morokuma S, Aiko Y, Senju A, et al.
Environ Health Prev Med
. 2019 Jun;
24(1):40.
PMID: 31174461
Background: Placenta previa and placenta accreta associate with high morbidity and mortality for both mothers and fetus. Metal exposure may have relationships with placenta previa and placenta accreta. This study...
5.
Hasunuma H, Yamazaki S, Tamura K, Hwang Y, Ono R, Amimoto Y, et al.
J Asthma
. 2018 Jan;
55(7):712-719.
PMID: 29309210
Objective: In recent years, air pollutant concentrations in Japan have decreased slightly; however, there are growing concerns about the influences of transnational air pollution on respiratory illness. We aimed to...
6.
Aiko Y, Askew D, Aramaki S, Myoga M, Tomonaga C, Hachisuga T, et al.
BMC Pregnancy Childbirth
. 2014 Jun;
14:181.
PMID: 24886642
Background: Sufficient amino acid transport activity (AAT) is indispensable for appropriate fetal growth. Studies suggest that placental nutrient uptake activity is responsive to both maternal and fetal nutrient demands. We...
7.
Sivaprasad U, Askew D, Ericksen M, Gibson A, Stier M, Brandt E, et al.
J Allergy Clin Immunol
. 2010 Dec;
127(1):254-61, 261.e1-6.
PMID: 21126757
Background: Asthma is a major public health burden worldwide. Studies from our group and others have demonstrated that SERPINB3 and SERPINB4 are induced in patients with asthma; however, their mechanistic...
8.
Reece S, Loddenkemper C, Askew D, Zedler U, Schommer-Leitner S, Stein M, et al.
J Clin Invest
. 2010 Aug;
120(9):3365-76.
PMID: 20679732
The hallmark of human Mycobacterium tuberculosis infection is the presence of lung granulomas. Lung granulomas can have different phenotypes, with caseous necrosis and hypoxia present within these structures during active...
9.
Aujla S, Chan Y, Zheng M, Fei M, Askew D, Pociask D, et al.
Nat Med
. 2008 Feb;
14(3):275-81.
PMID: 18264110
Emerging evidence supports the concept that T helper type 17 (T(H)17) cells, in addition to mediating autoimmunity, have key roles in mucosal immunity against extracellular pathogens. Interleukin-22 (IL-22) and IL-17A...
10.
Luke C, Pak S, Askew Y, Naviglia T, Askew D, Nobar S, et al.
Cell
. 2007 Sep;
130(6):1108-19.
PMID: 17889653
Extracellular serpins such as antithrombin and alpha1-antitrypsin are the quintessential regulators of proteolytic pathways. In contrast, the biological functions of the intracellular serpins remain obscure. We now report that the...