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David Gaudout

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Articles 25
Citations 240
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Recent Articles
1.
Bardinet J, Pouchieu C, Chuy V, Merle B, Pellay H, Lefevre-Arbogast S, et al.
Eur J Nutr . 2025 Feb; 64(2):88. PMID: 39932601
Purpose: Nutrition, as a modifiable exposure, seems relevant to prevent depression. Several nutrients have been associated with a lower risk of depression in older adults, but longitudinal studies examining nutrient...
2.
Connell E, Le Gall G, McArthur S, Lang L, Breeze B, Pontifex M, et al.
Neurochem Int . 2024 Oct; 180:105878. PMID: 39389472
The dynamic protective capacity of (poly)phenols, attributed to their potent antioxidant and anti-inflammatory properties, has been consistently reported. Due to their capacity to alter gut microbiome composition, further actions of...
3.
Martin M, Debenay E, Bardinet J, Peltier A, Pourtau L, Gaudout D, et al.
Inflamm Res . 2024 Sep; 73(11):2023-2042. PMID: 39340661
Objective And Design: Neuroinflammation is a protective mechanism but can become harmful if chronic and/or unregulated, leading to neuronal damage and cognitive alterations. Limiting inflammation and promoting resolution could be...
4.
Martin M, Boulaire M, Lucas C, Peltier A, Pourtau L, Gaudout D, et al.
J Nutr . 2024 Sep; 154(12):3704-3717. PMID: 39332773
Background: Aging, characterized by a slow and progressive alteration of cognitive functions, is associated with gut microbiota dysbiosis, low-grade chronic inflammation, as well as increased oxidative stress and neurofunctional alterations....
5.
Pontifex M, Connell E, Le Gall G, Lang L, Pourtau L, Gaudout D, et al.
Gut Microbes . 2024 Jun; 16(1):2363011. PMID: 38835220
The Mediterranean diet (MD) and its bioactive constituents have been advocated for their neuroprotective properties along with their capacity to affect gut microbiota speciation and metabolism. Mediated through the gut...
6.
Lang L, McArthur S, Lazar A, Pourtau L, Gaudout D, Pontifex M, et al.
Nutrients . 2024 May; 16(10). PMID: 38794738
As the population ages, the incidence of age-related neurodegenerative diseases is rapidly increasing, and novel approaches to mitigate this soaring prevalence are sorely needed. Recent studies have highlighted the importance...
7.
Vignault A, Vaysse C, Bertand K, Krisa S, Courtois A, Moras B, et al.
Metabolites . 2024 Apr; 14(4). PMID: 38668318
The therapeutic effects of saffron have been reported and described in relation to its major derivatives. Among them, in terms of saffron's properties, crocin and crocetin absorption and bioavailability have...
8.
Pourtau L, Wauquier F, Boutin-Wittrant L, Gaudout D, Moras B, Vignault A, et al.
Pharmaceutics . 2024 Mar; 16(3). PMID: 38543230
Safe and anti-inflammatory plant-based natural products present an increasing focus in the treatment of chronic inflammatory diseases such as osteoarthritis or inflammatory bowel diseases. Among them, saffron, a spice derived...
9.
Monchaux de Oliveira C, Morael J, Guille A, Amadieu C, Vancassel S, Gaudout D, et al.
Front Nutr . 2023 Oct; 10:1267839. PMID: 37867499
Background: Although activation of inflammatory processes is essential to fight infections, its prolonged impact on brain function is well known to contribute to the pathophysiology of many medical conditions, including...
10.
Bardinet J, Pouchieu C, Chuy V, Helmer C, Etheve S, Gaudout D, et al.
J Affect Disord . 2023 Jul; 339:615-623. PMID: 37467792
Background: As part of a healthy diet, higher carotenoid intakes have been associated with a reduced risk of depression, mainly in adults, while prospective studies on plasma carotenoids in older...