David Gaudout

Overview

Explore the profile of David Gaudout including associated specialties, affiliations and a list of published articles.

Snapshot

Articles 25

Citations 240

Followers 0

Related Specialties

Nutritional Sciences

Neurology

Chemistry

Top 10 Co-Authors

Line Pourtau

Camille Pouchieu

Lucile Capuron

David Vauzour

Veronique Pallet

Sophie Laye

Julien Bensalem

Nathalie Castanon

Benjamin Moras

Camille Monchaux de Oliveira

Published In

Nutrients

Pharmaceutics

Front Nutr

J Nutr

Eur J Nutr

Affiliations

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Recent Articles

11.

Acute Effect of a Saffron Extract (Safr'Inside) and Its Main Volatile Compound on the Stress Response in Healthy Young Men: A Randomized, Double Blind, Placebo-Controlled, Crossover Study

Pouchieu C, Pourtau L, Brossaud J, Gaudout D, Corcuff J, Capuron L, et al.

Nutrients . 2023 Jul; 15(13). PMID: 37447245

According to animal studies, saffron and its main volatile compound safranal may reduce biological and behavioral signs of acute stress. However, little is known about its impact in humans. This...

12.

Effects of a polyphenol-rich grape and blueberry extract (Memophenol™) on cognitive function in older adults with mild cognitive impairment: A randomized, double-blind, placebo-controlled study

Lopresti A, Smith S, Pouchieu C, Pourtau L, Gaudout D, Pallet V, et al.

Front Psychol . 2023 Apr; 14:1144231. PMID: 37063535

Background: Polyphenols are naturally occurring organic compounds found in plants. Research suggests that their intake reduces the risk of cognitive decline and related dementias. Grapes and blueberries are polyphenol-rich foods...

13.

Saffron extract (Safr'Inside™) improves anxiety related behaviour in a mouse model of low-grade inflammation through the modulation of the microbiota and gut derived metabolites

Pontifex M, Connell E, Le Gall G, Pourtau L, Gaudout D, Angeloni C, et al.

Food Funct . 2022 Nov; 13(23):12219-12233. PMID: 36341693

Treatment of anxiety and depression predominantly centres around pharmacological interventions, which have faced criticism for their associated side effects, lack of efficacy and low tolerability. Saffron, which is reportedly well...

14.

Patterns of polyphenol intake and risk of depressive symptomatology in a population-based cohort of older adults

Bardinet J, Pouchieu C, Pellay H, Lefevre-Arbogast S, Chuy V, Galera C, et al.

Clin Nutr . 2022 Oct; 41(12):2628-2636. PMID: 36308981

Background & Aims: Current evidence suggests that some isolated polyphenols (PP) may exert promising effects for the risk of depression in young adults, however studies among older adults remain limited....

15.

Authentication of Iranian Saffron () Using Stable Isotopes δC and δH and Metabolites Quantification

Moras B, Pouchieu C, Gaudout D, Rey S, Anchisi A, Saupin X, et al.

Molecules . 2022 Oct; 27(20). PMID: 36296396

Saffron is a very high value-added ingredient used in the food supplement market and contains a high level of safranal. Adding synthetic safranal to saffron, which is significantly cheaper, and...

16.

Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr'Inside) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders

Wauquier F, Boutin-Wittrant L, Pourtau L, Gaudout D, Moras B, Vignault A, et al.

Nutrients . 2022 Apr; 14(7). PMID: 35406124

Increases in oxidative stress have been reported to play a central role in the vulnerability to depression, and antidepressant drugs may reduce increased oxidative stress in patients. Among the plants...

17.

Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission

Monchaux de Oliveira C, De Smedt-Peyrusse V, Morael J, Vancassel S, Capuron L, Gaudout D, et al.

Pharmaceutics . 2021 Dec; 13(12). PMID: 34959434

Depressive disorders are a major public health concern. Despite currently available treatment options, their prevalence steadily increases, and a high rate of therapeutic failure is often reported, together with important...

18.

Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission

Monchaux de Oliveira C, Pourtau L, Vancassel S, Pouchieu C, Capuron L, Gaudout D, et al.

Nutrients . 2021 Apr; 13(3). PMID: 33799507

Depressive disorders represent a major public health concern and display a continuously rising prevalence. Importantly, a large proportion of patients develops aversive side effects and/or does not respond properly to...

19.

Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults: A Randomized, Double-Blind, Parallel Group, Clinical Trial

Jackson P, Forster J, Khan J, Pouchieu C, Dubreuil S, Gaudout D, et al.

Front Nutr . 2021 Feb; 7:606124. PMID: 33598475

Anxiety, stress, and low mood are closely related and may contribute to depressive symptoms. Among non-pharmacological solutions to improve subclinical mood symptoms and resilience to stress, natural products such as...

20.

Polyphenols From Grape and Blueberry Improve Episodic Memory in Healthy Elderly with Lower Level of Memory Performance: A Bicentric Double-Blind, Randomized, Placebo-Controlled Clinical Study

Bensalem J, Dudonne S, Etchamendy N, Pellay H, Amadieu C, Gaudout D, et al.

J Gerontol A Biol Sci Med Sci . 2018 Jul; 74(7):996-1007. PMID: 30032176

Polyphenols are promising nutritional bioactives exhibiting beneficial effect on age-related cognitive decline. This study evaluated the effect of a polyphenol-rich extract from grape and blueberry (PEGB) on memory of healthy...