David E Reichert
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Explore the profile of David E Reichert including associated specialties, affiliations and a list of published articles.
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48
Citations
626
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Recent Articles
1.
Yarava A, Marshall C, Reichert D, Ye A, Khanal P, Robbins S, et al.
J Clin Transl Sci
. 2024 Dec;
8(1):e200.
PMID: 39655012
Introduction: In response to the COVID-19 pandemic, we rapidly implemented a plasma coordination center, within two months, to support transfusion for two outpatient randomized controlled trials. The center design was...
2.
Baldelomar E, Zhang H, Thorek D, Charlton J, Walker P, Wilson L, et al.
ACS Appl Bio Mater
. 2024 Sep;
7(10):6392-6397.
PMID: 39241192
In this work, we develop recombinant human cationic ferritin (rHCF) as a contrast agent to detect glomeruli in the kidney using positron emission tomography (PET). We first expressed recombinant human...
3.
Baldelomar E, Emoto K, Jordan M, Charlton J, Reichert D, Parvin N, et al.
Methods Mol Biol
. 2023 Jul;
2664:201-213.
PMID: 37423992
Cationic ferritin (CF) has been developed as a multimodal, targeted imaging tracer to directly detect and map nephrons in the kidney in vivo. Direct detection of functional nephrons provides a...
4.
Krishnan K, Qian M, Feltes M, Chen Z, Gale S, Wang L, et al.
ACS Chem Biol
. 2021 Aug;
16(8):1493-1507.
PMID: 34355883
Aliphatic diazirine analogues of cholesterol have been used previously to elaborate the cholesterol proteome and identify cholesterol binding sites on proteins. Cholesterol analogues containing the trifluoromethylphenyl diazirine (TPD) group have...
5.
Germann A, Pierce S, Tateiwa H, Sugasawa Y, Reichert D, Evers A, et al.
Mol Pharmacol
. 2021 May;
100(1):19-31.
PMID: 33958479
Prior work employing functional analysis, photolabeling, and X-ray crystallography have identified three distinct binding sites for potentiating steroids in the heteromeric GABA receptor. The sites are located in the membrane-spanning...
6.
Baldelomar E, Reichert D, Shoghi K, Beeman S, Charlton J, Strong L, et al.
Am J Physiol Renal Physiol
. 2020 Dec;
320(2):F183-F192.
PMID: 33283644
Nephron number varies widely in humans. A low nephron endowment at birth or a loss of functioning nephrons is strongly linked to increased susceptibility to chronic kidney disease. In this...
7.
Sugasawa Y, Cheng W, Bracamontes J, Chen Z, Wang L, Germann A, et al.
Elife
. 2020 Sep;
9.
PMID: 32955433
This study examines how site-specific binding to three identified neurosteroid-binding sites in the αβ GABA receptor (GABAR) contributes to neurosteroid allosteric modulation. We found that the potentiating neurosteroid, allopregnanolone, but...
8.
Germann A, Reichert D, Burbridge A, Pierce S, Evers A, Steinbach J, et al.
Mol Pharmacol
. 2020 Jul;
98(4):280-291.
PMID: 32675382
The 1 GABA receptor is prominently expressed in the retina and is present at lower levels in several brain regions and other tissues. Although the 1 receptor is insensitive to...
9.
Sugasawa Y, Bracamontes J, Krishnan K, Covey D, Reichert D, Akk G, et al.
J Steroid Biochem Mol Biol
. 2019 Jun;
192:105383.
PMID: 31150831
Neurosteroids positively modulate GABA-A receptor (GABAR) channel activity by binding to a transmembrane domain intersubunit site. Understanding the interactions in this site that determine neurosteroid binding and its effect is...
10.
Heo G, Zhao Y, Sultan D, Zhang X, Detering L, Luehmann H, et al.
ACS Appl Mater Interfaces
. 2019 May;
11(22):19669-19678.
PMID: 31074257
Nanoparticles have been widely used for preclinical cancer imaging. However, their successful clinical translation is largely hampered by potential toxicity, unsatisfactory detection of malignancy at early stages, inaccurate diagnosis of...