David Chiovitti
Overview
Explore the profile of David Chiovitti including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
258
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Xiong S, Lorenzen K, Couzens A, Templeton C, Rajendran D, Mao D, et al.
Structure
. 2018 Jul;
26(8):1101-1115.e6.
PMID: 29983373
The human NDR family kinases control diverse aspects of cell growth, and are regulated through phosphorylation and association with scaffolds such as MOB1. Here, we report the crystal structure of...
2.
Sanches M, Duffy N, Talukdar M, Thevakumaran N, Chiovitti D, Canny M, et al.
Nat Commun
. 2014 Aug;
5:4202.
PMID: 25164867
Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA...
3.
Wan L, Mao D, Neculai D, Strecker J, Chiovitti D, Kurinov I, et al.
Nucleic Acids Res
. 2013 Apr;
41(12):6332-46.
PMID: 23620299
The universally conserved Kae1/Qri7/YgjD and Sua5/YrdC protein families have been implicated in growth, telomere homeostasis, transcription and the N6-threonylcarbamoylation (t(6)A) of tRNA, an essential modification required for translational fidelity by...
4.
Dey M, Velyvis A, Li J, Chiu E, Chiovitti D, Kay L, et al.
Proc Natl Acad Sci U S A
. 2011 Mar;
108(11):4316-21.
PMID: 21368187
As phosphorylation of eukaryotic translation initiation factor 2α (eIF2α) on Ser51 inhibits protein synthesis, cells restrict this phosphorylation to the antiviral protein kinase PKR and related eIF2α kinases. In the...
5.
Volkmann K, Lucas J, Vuga D, Wang X, Brumm D, Stiles C, et al.
J Biol Chem
. 2011 Feb;
286(14):12743-55.
PMID: 21303903
Inositol-requiring enzyme 1 (IRE1) is the most highly conserved signaling node of the unfolded protein response (UPR) and represents a potential therapeutic target for a number of diseases associated with...