Julie L Lucas
Overview
Explore the profile of Julie L Lucas including associated specialties, affiliations and a list of published articles.
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5
Citations
245
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Recent Articles
1.
Lucas J, Tacheny E, Ferris A, Galusha M, Srivastava A, Ganguly A, et al.
PLoS One
. 2017 Aug;
12(8):e0182739.
PMID: 28771597
Cancer therapies can provide substantially improved survival in some patients while other seemingly similar patients receive little or no benefit. Strategies to identify patients likely to respond well to a...
2.
Sanches M, Duffy N, Talukdar M, Thevakumaran N, Chiovitti D, Canny M, et al.
Nat Commun
. 2014 Aug;
5:4202.
PMID: 25164867
Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA...
3.
Volkmann K, Lucas J, Vuga D, Wang X, Brumm D, Stiles C, et al.
J Biol Chem
. 2011 Feb;
286(14):12743-55.
PMID: 21303903
Inositol-requiring enzyme 1 (IRE1) is the most highly conserved signaling node of the unfolded protein response (UPR) and represents a potential therapeutic target for a number of diseases associated with...
4.
Lucas J, Mirshahpanah P, Haas-Stapleton E, Asadullah K, Zollner T, Numerof R
Cell Immunol
. 2009 Apr;
257(1-2):97-104.
PMID: 19358983
Histone deacetylase inhibitors are under investigation in the clinic as a new class of anti-cancer therapeutics. While recent studies have also suggested their potential as inhibitors of a wide spectrum...
5.
Lucas J, Wang D, Sadee W
Pharm Res
. 2006 Mar;
23(4):647-53.
PMID: 16552497
Purpose: This study was conducted to identify and characterize the structural requirements of a calmodulin-binding motif identified in the third intracellular (i3) loop of muscarinic acetylcholine receptors (M1-M5), a region...