David C Loch
Overview
Explore the profile of David C Loch including associated specialties, affiliations and a list of published articles.
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Articles
5
Citations
236
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0
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Recent Articles
1.
Gallo E, Loch D, Habashi J, Calderon J, Chen Y, Bedja D, et al.
J Clin Invest
. 2013 Dec;
124(1):448-60.
PMID: 24355923
Loeys-Dietz syndrome (LDS) is a connective tissue disorder that is characterized by a high risk for aneurysm and dissection throughout the arterial tree and phenotypically resembles Marfan syndrome. LDS is...
2.
Loch D, Pollock P
Cancer Discov
. 2012 Dec;
2(12):1081-3.
PMID: 23230185
In this issue of Cancer Discovery, Guagnano and colleagues use a large and diverse annotated collection of cancer cell lines, the Cancer Cell Line Encyclopedia, to correlate whole-genome expression and...
3.
Byron S, Loch D, Pollock P
Int J Gynecol Cancer
. 2012 Oct;
22(9):1517-26.
PMID: 23060048
Objective: The fibroblast growth factor (FGF) family of signaling molecules has been associated with chemoresistance and poor prognosis in a number of cancer types, including lung, breast, ovarian, prostate, and...
4.
Byron S, Loch D, Wellens C, Wortmann A, Wu J, Wang J, et al.
Mol Cancer
. 2012 Oct;
11:75.
PMID: 23039341
Background: Melanoma is the most lethal form of skin cancer, but recent advances in molecularly targeted agents against the Ras/Raf/MAPK pathway demonstrate promise as effective therapies. Despite these advances, resistance...
5.
Arachidonic acid metabolism as a potential mediator of cardiac fibrosis associated with inflammation
Levick S, Loch D, Taylor S, Janicki J
J Immunol
. 2007 Jan;
178(2):641-6.
PMID: 17202322
An increase in left ventricular collagen (cardiac fibrosis) is a detrimental process that adversely affects heart function. Strong evidence implicates the infiltration of inflammatory cells as a critical part of...