David A Rudnick
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Explore the profile of David A Rudnick including associated specialties, affiliations and a list of published articles.
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44
Citations
933
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Recent Articles
1.
Cohen S, Yerushalmy-Feler A, Rojas I, Phen C, Rudnick D, Flahive C, et al.
J Pediatr Gastroenterol Nutr
. 2024 May;
79(1):161-167.
PMID: 38801072
Objective: A constitutional disease-causing variant (DCV) in the SMAD4 or BMPR1A genes is present in 40%-60% of patients with juvenile polyposis syndrome (JPS). The aim of this study was to...
2.
Rudnick D
Cell Mol Gastroenterol Hepatol
. 2024 Jan;
17(3):501-502.
PMID: 38169193
No abstract available.
3.
Kulkarni S, Chapin C, Alonso E, Rudnick D
Clin Liver Dis
. 2022 Jul;
26(3):461-471.
PMID: 35868685
Pediatric acute liver failure (PALF) is a complex, unpredictable, often rapidly progressive, potentially devastating clinical syndrome that occurs in infants, children, and adolescents without pre-existing liver disease. PALF is characterized...
4.
Kulkarni S, Goss C, Khan A, Nadler M, Stoll J, Doyle M, et al.
J Pediatr Gastroenterol Nutr
. 2022 Apr;
74(6):750-756.
PMID: 35442235
Background: We characterized recent outcomes in US pediatric acute liver failure (PALF) subjects listed for liver transplantation (LT) using the Scientific Registry of Transplant Recipients (SRTR) database. Methods: Pediatric subjects...
5.
Rudnick D, Huang J, Hidvegi T, Chu A, Hale P, Munanairi A, et al.
Gastroenterology
. 2022 Mar;
163(1):270-284.
PMID: 35301011
Background & Aims: Insulin signaling is known to regulate essential proteostasis mechanisms. Methods: The analyses here examined effects of insulin signaling in the PiZ mouse model of α1-antitrypsin deficiency in...
6.
Pihlajoki M, Soini T, Cochran R, Liljestrom E, Huang J, Rudnick D, et al.
Hepatol Int
. 2021 Jan;
15(1):166-178.
PMID: 33486744
Background: GATA6, a transcription factor expressed in cholangiocytes, has been implicated in the response to liver injury. In biliary atresia, a disease characterized by extrahepatic bile duct obstruction, liver expression...
7.
Kulkarni S, Huang J, Tycksen E, Cliften P, Rudnick D
PPAR Res
. 2020 Sep;
2020:3817573.
PMID: 32963510
Pioglitazone (Pio) is a thiazolidinedione (TZD) insulin-sensitizing drug whose effects result predominantly from its modulation of the transcriptional activity of peroxisome proliferator-activated-receptor-gamma (PPAR). Pio is used to treat human insulin-resistant...
8.
Wilson D, Rudnick D
Am J Pathol
. 2019 Jun;
189(8):1501-1504.
PMID: 31202722
This commentary highlights the article by Clerbaux et al that describes the critical role of invasive ductular reaction in hepatocellular injury.
9.
10.
Liver Transplant Listing in Pediatric Acute Liver Failure: Practices and Participant Characteristics
Squires J, Rudnick D, Hardison R, Horslen S, Ng V, Alonso E, et al.
Hepatology
. 2018 Aug;
68(6):2338-2347.
PMID: 30070372
Liver transplant (LT) decisions in pediatric acute liver failure (PALF) are complex. Three phases of the PALF registry, containing data on 1,144 participants over 15 years, were interrogated to characterize...