Dennis J Dietzen
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Explore the profile of Dennis J Dietzen including associated specialties, affiliations and a list of published articles.
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85
Citations
1124
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Recent Articles
1.
Lalos N, Vesoulis Z, Maucione C, Eby C, Dietzen D, Roper S, et al.
J Thromb Haemost
. 2024 Sep;
22(12):3473-3478.
PMID: 39271017
Background: Interpretation of coagulation testing in neonates currently relies on reference intervals (RIs) defined from older patient cohorts. Direct RI studies are difficult, but indirect estimation may allow us to...
2.
Zhang Y, Higgins C, Tica S, Adams J, Sun J, Kelly S, et al.
Cell Metab
. 2024 Aug;
36(9):2069-2085.e8.
PMID: 39116884
Urea cycle impairment and its relationship to obesity and inflammation remained elusive, partly due to the dramatic clinical presentation of classical urea cycle defects. We generated mice with hepatocyte-specific arginase...
3.
Omosule C, Blair C, Herries E, Zaydman M, Farnsworth C, Ladenson J, et al.
Clin Chem
. 2024 Aug;
70(9):1172-1181.
PMID: 39092926
Background: Diagnosing acute kidney injury (AKI) and chronic kidney disease (CKD) relies on creatinine, which lacks optimal diagnostic sensitivity. The kidney-specific proximal tubular enzyme myo-inositol oxygenase (MIOX) catalyzes the conversion...
4.
Mishra S, Kell P, Scherrer D, Dietzen D, Vite C, Berry-Kravis E, et al.
J Lipid Res
. 2024 Jul;
65(8):100600.
PMID: 39048052
Lysosomal function is impaired in Niemann-Pick disease type C1 (NPC1), a rare and inherited neurodegenerative disorder, resulting in late endosomal/lysosomal accumulation of unesterified cholesterol. The precise pathogenic mechanism of NPC1...
5.
Friedman K, Bohm-Weigert M, DeSimone N, Dietzen D, Eby C, Flickinger C, et al.
Res Pract Thromb Haemost
. 2024 Jun;
8(4):102422.
PMID: 38840662
Background: To overcome deficiencies of the traditional von Willebrand factor (VWF) ristocetin cofactor activity assay (VWF:RCo), several automated assays for VWF platelet-binding activity have been developed. Information on the performance...
6.
Anastasaki C, Chatterjee J, Koleske J, Gao Y, Bozeman S, Kernan C, et al.
Neuro Oncol
. 2024 Apr;
26(8):1496-1508.
PMID: 38607967
Background: With the recognition that noncancerous cells function as critical regulators of brain tumor growth, we recently demonstrated that neurons drive low-grade glioma initiation and progression. Using mouse models of...
7.
Dietzen D, Jackups R, Zaydman M
Clin Chim Acta
. 2024 Mar;
557:117862.
PMID: 38460583
Background: Analysis of whole blood specimens is rapid and saves blood, but hemolysis may go undetected and compromise the accuracy of potassium measurement. We aimed to define the frequency and...
8.
Brown H, Roper S, Dietzen D, Crews B
J Anal Toxicol
. 2023 Nov;
48(2):99-103.
PMID: 37952088
Current guidelines recommend universal screening for substance use disorders in obstetric patients, and neonatal drug testing is also frequently performed. Meconium is often the preferred specimen type to detect neonatal...
9.
Omosule C, Dietzen D, Roper S
J Appl Lab Med
. 2023 Sep;
8(6):1084-1091.
PMID: 37757465
Background: Guidelines for sweat chloride testing endorse a minimum sweat rate for reporting results. Bilateral sweat collection is recommended, but if both sites fail to meet the minimum rate (quantity...
10.
Kell P, Sidhu R, Qian M, Mishra S, Nicoli E, DSouza P, et al.
EBioMedicine
. 2023 Jun;
92:104627.
PMID: 37267847
Background: GM1 gangliosidosis is a rare, fatal, neurodegenerative disease caused by mutations in the GLB1 gene and deficiency in β-galactosidase. Delay of symptom onset and increase in lifespan in a...