David A Lawrence
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Explore the profile of David A Lawrence including associated specialties, affiliations and a list of published articles.
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126
Citations
2487
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Recent Articles
21.
Emeny R, Carpenter D, Lawrence D
Toxicol Appl Pharmacol
. 2021 Feb;
416:115444.
PMID: 33549591
Health disparities exist dependent on socioeconomic status, living conditions, race/ethnicity, diet, and exposures to environmental pollutants. Herein, the various exposures contributing to a person's exposome are collectively considered social determinants...
22.
Uddin M, Yao Y, Manley K, Lawrence D
Cell Immunol
. 2020 Nov;
358:104223.
PMID: 33137646
Autism spectrum disorder (ASD) is a complex neurodevelopmental condition that is characterized by a lack of social interaction, decreased verbal and non-verbal communication skills, and stereotyped repetitive behavior. There is...
23.
Yao Y, Lawrence D
J Biochem Mol Toxicol
. 2020 Sep;
35(1):e22626.
PMID: 32905655
SARS-CoV-2 is a novel betacoronavirus that has caused the global health crisis known as COVID-19. The implications of mitochondrial dysfunction with COVID-19 are discussed as well as deregulated mitochondria and...
24.
Kasten-Jolly J, Lawrence D
Curr Protoc Toxicol
. 2020 Jun;
84(1):e95.
PMID: 32539242
Culture of human peripheral blood mononuclear cells (PBMCs) still remains a convenient and sensitive method for measurement of a person's immune system health. Basic elements of the process, namely PBMC...
25.
Harnoss J, Le Thomas A, Reichelt M, Guttman O, Wu T, Marsters S, et al.
Cancer Res
. 2020 Apr;
80(11):2368-2379.
PMID: 32265225
Cancer cells exploit the unfolded protein response (UPR) to mitigate endoplasmic reticulum (ER) stress caused by cellular oncogene activation and a hostile tumor microenvironment (TME). The key UPR sensor IRE1α...
26.
Hongsmatip P, Cheng K, Kim C, Lawrence D, Rivera R, Smitaman E
Eur J Radiol
. 2019 Sep;
120:108653.
PMID: 31550638
Objective: Calcium hydroxyapatite depositional disease (HADD) is usually asymptomatic and self-limiting; however, when there is an associated inflammatory process or HADD occurs in an unusual location, it may mimic trauma,...
27.
Shemorry A, Harnoss J, Guttman O, Marsters S, Komuves L, Lawrence D, et al.
Elife
. 2019 Aug;
8.
PMID: 31453810
Upon detecting endoplasmic reticulum (ER) stress, the unfolded protein response (UPR) orchestrates adaptive cellular changes to reestablish homeostasis. If stress resolution fails, the UPR commits the cell to apoptotic death....
28.
Harnoss J, Le Thomas A, Shemorry A, Marsters S, Lawrence D, Lu M, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(33):16420-16429.
PMID: 31371506
Multiple myeloma (MM) arises from malignant immunoglobulin (Ig)-secreting plasma cells and remains an incurable, often lethal disease despite therapeutic advances. The unfolded-protein response sensor IRE1α supports protein secretion by deploying...
29.
Kasten-Jolly J, Lawrence D
J Toxicol Environ Health B Crit Rev
. 2019 Mar;
21(6-8):400-413.
PMID: 30917763
The environmental toxicant lead (Pb) and the essential element calcium (Ca) play an interactive role in extracellular and intracellular regulatory functions that affect health. Lead's usurping calcium binding sites, as...
30.
Adeyeye T, Yeung E, McLain A, Lin S, Lawrence D, Bell E
Am J Epidemiol
. 2018 Nov;
188(2):355-362.
PMID: 30475936
We examined whether cesarean delivery (CD) increased the risk of wheeze or food allergy in early childhood compared with vaginal delivery and whether these associations were mediated by breastfeeding. The...