Darrell Kotton
Overview
Explore the profile of Darrell Kotton including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
1289
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Yampolskaya M, Herriges M, Ikonomou L, Kotton D, Mehta P
bioRxiv
. 2023 Feb;
PMID: 36747864
Advances in single-cell RNA-sequencing (scRNA-seq) provide an unprecedented window into cellular identity. The increasing abundance of data requires new theoretical and computational frameworks for understanding cell fate determination, accurately classifying...
2.
Generation of Airway Epithelial Cell Air-Liquid Interface Cultures from Human Pluripotent Stem Cells
Berical A, Beermann M, Suzuki S, LeSuer J, Matte T, Davis B, et al.
J Vis Exp
. 2022 Jul;
(184).
PMID: 35781291
Diseases of the conducting airway such as asthma, cystic fibrosis (CF), primary ciliary dyskinesia (PCD), and viral respiratory infections are major causes of morbidity and mortality worldwide. In vitro platforms...
3.
Kotton D
Regen Med
. 2017 Jun;
12(4):337-338.
PMID: 28621167
Dr Kotton is the David Seldin Professor of Medicine and the founding Director of the Center for Regenerative Medicine of Boston University and Boston Medical Center. He conducts basic stem...
4.
Weiss D, Chambers D, Giangreco A, Keating A, Kotton D, Lelkes P, et al.
Ann Am Thorac Soc
. 2015 Apr;
12(4):S79-97.
PMID: 25897748
The University of Vermont College of Medicine and the Vermont Lung Center, in collaboration with the NHLBI, Alpha-1 Foundation, American Thoracic Society, European Respiratory Society, International Society for Cell Therapy,...
5.
West J, Austin E, Gaskill C, Marriott S, Baskir R, Bilousova G, et al.
Am J Physiol Cell Physiol
. 2014 May;
307(5):C415-30.
PMID: 24871858
Understanding differences in gene expression that increase risk for pulmonary arterial hypertension (PAH) is essential to understanding the molecular basis for disease. Previous studies on patient samples were limited by...
6.
Sahin E, Colla S, Liesa M, Moslehi J, Muller F, Guo M, et al.
Nature
. 2011 Feb;
470(7334):359-65.
PMID: 21307849
Telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis to drive progressive atrophy and functional decline in high-turnover tissues. The broader adverse impact of telomere dysfunction across many tissues...
7.
Novak A, Shtrichman R, Germanguz I, Segev H, Zeevi-Levin N, Fishman B, et al.
Cell Reprogram
. 2010 Oct;
12(6):665-78.
PMID: 20964482
Induced pluripotent stem cells (iPSCs) represent an ideal cell source for future cell therapy and regenerative medicine. However, most iPSC lines described to date have been isolated from skin fibroblasts...
8.
Ott H, Clippinger B, Conrad C, Schuetz C, Pomerantseva I, Ikonomou L, et al.
Nat Med
. 2010 Jul;
16(8):927-33.
PMID: 20628374
About 2,000 patients now await a donor lung in the United States. Worldwide, 50 million individuals are living with end-stage lung disease. Creation of a bioartificial lung requires engineering of...
9.
Wu J, Qian J, Li C, Kwok L, Cheng F, Liu P, et al.
Cell Cycle
. 2010 Apr;
9(9):1809-18.
PMID: 20404570
Reduced expression of miR-129 has been reported in multiple tumor cell lines and in primary tumors including medulloblastoma, undifferentiated gastric cancers, lung adenocarcinoma, endometrial cancer and colorectal carcinoma. There is...
10.
Cao Y, Vo T, Millien G, Tagne J, Kotton D, Mason R, et al.
J Biol Chem
. 2009 Nov;
285(3):2152-64.
PMID: 19906647
Epigenetic regulation of transcription plays an important role in cell-specific gene expression by altering chromatin structure and access of transcriptional regulators to DNA binding sites. Surfactant protein B (Sftpb) is...