Darrel E Goll
Overview
Explore the profile of Darrel E Goll including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
161
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Neti G, Novak S, Thompson V, Goll D
Am J Physiol Cell Physiol
. 2009 Mar;
296(6):C1383-90.
PMID: 19321741
Myofibrillar proteins must be removed from the myofibril before they can be turned over metabolically in functioning muscle cells. It is uncertain how this removal is accomplished without disruption of...
2.
Purification and characterization of calpain and calpastatin from rainbow trout, Oncorhynchus mykiss
Saito M, Li H, Thompson V, Kunisaki N, Goll D
Comp Biochem Physiol B Biochem Mol Biol
. 2007 Feb;
146(4):445-55.
PMID: 17276714
Although the calpain system has been studied extensively in mammalian animals, much less is known about the properties of mu-calpain, m-calpain, and calpastatin in lower vertebrates such as fish. These...
3.
Zalewska T, Thompson V, Goll D
Biochim Biophys Acta
. 2004 Aug;
1693(2):125-33.
PMID: 15313014
The finding that phospholipid micelles lowered the Ca2+ concentration required for autolysis of the calpains led to a hypothesis suggesting that the calpains are translocated to the plasma membrane where...
4.
Wendt A, Thompson V, Goll D
Biol Chem
. 2004 Jul;
385(6):465-72.
PMID: 15255177
Calpastatin is a multiheaded inhibitor capable of inhibiting more than one calpain molecule. Each inhibitory domain of calpastatin has three subdomains, A, B, and C; A binds to domain IV...
5.
Li H, Thompson V, Goll D
Biochim Biophys Acta
. 2004 Apr;
1691(2-3):91-103.
PMID: 15110990
Although the biochemical changes that occur during autolysis of mu- and m-calpain are well characterized, there have been few studies on properties of the autolyzed calpain molecules themselves. The present...
6.
Thompson V, Lawson K, Barlow J, Goll D
Biochim Biophys Acta
. 2003 May;
1648(1-2):140-53.
PMID: 12758157
Proteolytic digestion by trypsin and chymotrypsin was used to probe conformation and domain structure of the mu- and m-calpain molecules in the presence and the absence of Ca(2+). Both calpains...
7.
Thompson V, Saldana S, Cong J, Luedke D, Goll D
Life Sci
. 2002 Aug;
70(21):2493-508.
PMID: 12173413
The calpain system is involved in a number of human pathologies ranging from the muscular dystrophies to Alzheimer's disease. It is important, therefore, to be able to obtain and to...
8.
Cong J, Thompson V, Goll D
Protein Expr Purif
. 2002 Jul;
25(2):283-90.
PMID: 12135561
A monoclonal antibody to the small subunit common to both mu- and m-calpains can be used in an immunoaffinity column to purify either mu- or m-calpain in a proteolytically active...
9.
Wei W, Li H, Cong J, Thompson V, Goll D
Biochim Biophys Acta
. 2002 May;
1597(1):97-106.
PMID: 12009408
It has been difficult to purify calpastatin without using a step involving heating to 90-100 degrees C. Preparations of calpastatin obtained after heating often contain several polypeptides that have been...
10.
Kulkarni S, Goll D, Fox J
J Biol Chem
. 2002 Apr;
277(27):24435-41.
PMID: 11964413
Integrin-induced cell adhesion results in transmission of signals that induce cytoskeletal reorganizations and resulting changes in cell behavior. The cytoskeletal reorganizations are regulated by transient activation and inactivation of Rho...