Joan E B Fox
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Explore the profile of Joan E B Fox including associated specialties, affiliations and a list of published articles.
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12
Citations
196
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Recent Articles
1.
OToole T, Bialkowska K, Li X, Fox J
J Cell Physiol
. 2011 Feb;
226(11):2965-78.
PMID: 21302295
14-3-3 is an adaptor protein that localizes to the leading edge of spreading cells, returning to the cytoplasm as spreading ceases. Previously, we showed that integrin-induced Rac1 activation and spreading...
2.
Hoang M, Nagy J, Fox J, Senger D
PLoS One
. 2010 Nov;
5(10):e13612.
PMID: 21049044
Background: Successful neovascularization requires that sprouting endothelial cells (ECs) integrate to form new vascular networks. However, architecturally defective, poorly integrated vessels with blind ends are typical of pathological angiogenesis induced...
3.
Podolnikova N, OToole T, Haas T, Lam S, Fox J, Ugarova T
Biochemistry
. 2009 Jan;
48(3):617-29.
PMID: 19117493
Integrin alpha(IIb)beta(3) plays a pivotal role in hemostasis and thrombosis by mediating adhesive interactions of platelets. Binding of alpha(IIb)beta(3) to its physiological ligands, immobilized fibrinogen and fibrin, induces outside-in signaling...
4.
Reddy K, Fox J, Price M, Kulkarni S, Gupta S, Das B, et al.
J Muscle Res Cell Motil
. 2008 Jun;
29(1):1-8.
PMID: 18521710
Myomesin-I (also known as Skelemin) is a approximately 185 kDa protein, which is highly expressed in striated muscle. It contains the prototypic class-I (type-III fibronectin) and class-II (C2-immunoglobulin) motifs. Previous...
5.
Deshmukh L, Tyukhtenko S, Liu J, Fox J, Qin J, Vinogradova O
J Biol Chem
. 2007 Sep;
282(44):32349-56.
PMID: 17804417
Skelemin is a large cytoskeletal protein critical for cell morphology. Previous studies have suggested that its two-tandem immunoglobulin C2-like repeats (SkIgC4 and SkIgC5) are involved in binding to integrin beta3...
6.
Hewson M, Copeland H, Mascha E, Arrigain S, Topol E, Fox J
Patient Educ Couns
. 2006 Jun;
62(1):5-12.
PMID: 16766243
Objective: To meet the increasing patient interest in complementary and alternative medicine (CAM), conventional physicians need to understand CAM, be willing to talk with their patients about CAM, and be...
7.
Bialkowska K, Saido T, Fox J
J Cell Sci
. 2005 Jan;
118(Pt 2):381-95.
PMID: 15632109
In this study, we used cultured cells spreading on beta3 integrin substrates to examine the possibility that spectrin is involved in signal transduction. Spectrin clustered with specialized calpain-induced beta3 integrin...
8.
Kanaji T, Russell S, Cunningham J, Izuhara K, Fox J, Ware J
Blood
. 2004 Jul;
104(10):3161-8.
PMID: 15271795
We have investigated the ability of glycoprotein (GP) Ibalpha, a megakaryocytic gene product, to sequester the signal transduction protein 14-3-3xi and to influence megakaryocytopoiesis. Using a Gp1ba(-/-) mouse colony, we...
9.
Bialkowska K, Zaffran Y, Meyer S, Fox J
J Biol Chem
. 2003 Jun;
278(35):33342-50.
PMID: 12810725
Integrin-induced cytoskeletal reorganizations are initiated by Cdc42 and Rac1 but little is known about mechanisms by which integrins activate these Rho GTPases. 14-3-3 proteins are adaptors implicated in binding and...
10.
Austin R, Fox J, Werstuck G, Stafford A, Bulman D, Dally G, et al.
J Biol Chem
. 2002 Oct;
277(49):47106-13.
PMID: 12370193
Utrophin is a component of the platelet membrane cytoskeleton and participates in cytoskeletal reorganization (Earnest, J. P., Santos, G. F., Zuerbig, S., and Fox, J. E. B. (1995) J. Biol....